SPINAL CORD INJURY

This study follows 16 people for five years after they received an experimental gene therapy called EG110A for bladder control problems caused by spinal cord injury. Researchers want to understand the long-term safety of this treatment and see how long its benefits last. Particip…

This study is testing whether a lab-made stem cell product called XS228 can help repair nerve damage and improve movement in people with recent spinal cord injuries. About 60 adults with injuries that occurred 2-12 weeks ago will receive either the stem cell injection or a placeb…

This study is testing a non-invasive medical device called the SSMD to see if it is safe and can help improve arm movement and daily function in adults. It is for people who have had a stroke, brain injury, spinal cord injury, or nerve damage within the last two years. The device…

This study is testing a new robotic exoskeleton called the XoMotion-R that helps people with spinal cord injuries walk without needing to hold onto walkers or crutches. Sixteen participants, both in the hospital and living at home, will use the device during their rehabilitation …

This study is testing whether using a robotic exoskeleton to help people with chronic spinal cord injury walk, combined with a mild electrical stimulation on the spine, can improve their muscle size and bone strength. Researchers will compare the effects of real spinal stimulatio…

This study is testing whether adding gentle electrical stimulation to the spine during walking therapy helps people recover leg movement better after a recent spinal cord injury. Researchers will compare the combination therapy to walking therapy alone in 40 participants who are …

This early-stage study is testing whether a treatment made from a patient's own concentrated growth factors can help restore movement, sensation, and bodily functions after a spinal cord injury. Ten adults with recent or long-standing spinal cord injuries will have the growth fac…

This study is testing a new, non-invasive spinal stimulation device that uses artificial intelligence. The device aims to improve walking ability in people with incomplete spinal cord injuries by adjusting its electrical pulses in real-time based on the person's muscle signals an…

This study is testing a home-based therapy program for people with chronic spinal cord injuries that cause arm and hand weakness (tetraplegia). The program combines a gentle, non-invasive electrical stimulation device worn on the back with a smartphone app that guides daily arm e…

This study is testing a new therapy to help people with chronic spinal cord injury walk better. Researchers will combine a brief, loud sound with electrical leg stimulation and walking training to try and activate hidden nerve pathways. The goal is to see if this combination impr…

This study aims to improve hand and grasping function for people with chronic cervical spinal cord injuries. Researchers will test a combination of non-invasive brain stimulation and targeted hand exercise training. The goal is to strengthen remaining nerve connections to help pa…

This study is testing the safety and early effectiveness of a surgically implanted electrical stimulation device called ARC-IM Therapy. It aims to help people with recent or long-term spinal cord injuries recover walking and balance functions. The trial will enroll 12 participant…

This study is testing whether a smartphone app powered by artificial intelligence (AI) can help people with spinal cord injury better manage their bowel problems. The app provides personalized education and training. Researchers will see if using the app for 12 weeks reduces bowe…

This study is creating a training program to help veterans with spinal cord injuries and bladder problems communicate better with their doctors. The goal is to prevent these veterans from receiving antibiotics when they don't actually have an infection, which happens often. By em…

This study is testing a new live, online group exercise program called TEEMS, designed specifically for people with spinal cord injury. It will compare TEEMS to using a library of pre-recorded exercise videos to see which approach better helps participants feel more confident, be…

This study aims to see if a home-based shoulder strength training program can improve shoulder health and reduce pain for people who use manual wheelchairs after a recent spinal cord injury. Researchers will test whether starting the training 3 months or 12 months after leaving r…

This study is testing an online program called EmpowerSpine, designed to help people with spinal cord injuries manage their chronic pain. Researchers want to figure out which parts of the program—like coaching, peer support, or follow-up sessions—work best to reduce pain and impr…

This study aims to improve a portable brain-computer interface (BCI) device that helps people with paralysis control computers and mobile devices using their thoughts. Two veterans with conditions like spinal cord injury or ALS will test the device at home to see if new software …

This study aims to see if psilocybin, the active compound in 'magic mushrooms,' is safe and tolerable for people with spinal cord injuries who also have depression. Researchers will give 30 veterans with spinal cord injuries different doses of psilocybin to check for side effects…

This study aims to find out if a specialized arm-crank training method works better than standard strength training for people recovering from a recent spinal cord injury. Twenty participants will complete 20 training sessions over 12 weeks and be tested on their strength, endura…

This study is testing whether a specific type of talk therapy can help improve mental health and quality of life for people who have recently suffered a spinal cord injury. Eight patients recovering in the hospital will receive the therapy and answer questions about their mood an…

This study aims to learn more about people with spinal cord injuries by looking at past patient records. Researchers will review the medical files of 50 patients to understand what caused their injuries and what other health problems they developed. The goal is to gather informat…

This study aims to understand how stroke or spinal cord injury affects the Achilles tendon and calf muscle during walking. Researchers will measure tendon stiffness, muscle strength, and walking patterns in 60 participants (40 with neurological conditions and 20 healthy volunteer…