SPINAL CORD INJURY

This study tests a single injection of lab-made nerve cells (XS228) into the spinal fluid of 60 adults who had a spinal cord injury 2-12 weeks ago. The goal is to see if it safely improves movement, sensation, and bladder/bowel control. Participants are randomly assigned to recei…

This study will test a self-balancing exoskeleton called XoMotion-R in 16 people with spinal cord injury (SCI) who have some movement in their legs. The device allows users to walk hands-free, which could help those with limited arm function. Researchers want to see if it is safe…

This study tests whether walking in a robotic exoskeleton combined with mild electrical stimulation of the spinal cord can improve muscle and bone health in people with long-term spinal cord injury. 24 non-walking participants will be assigned to either active or sham stimulation…

This study tests a medical device called SSMD that uses gentle stimulation to help people with movement problems caused by stroke, traumatic brain injury, spinal cord injury, or nerve damage. About 120 adults aged 18 to 80 will use the device for 3 weeks to see if it improves arm…

This study tests whether combining loud sounds and mild electrical stimulation with walking practice can improve walking speed and leg strength in people with chronic spinal cord injury. About 20 adults with incomplete spinal cord injury will take part. The goal is to activate hi…

This early study is testing whether a patient's own concentrated growth factors can help restore movement, sensation, and bodily functions after spinal cord injury. Ten participants will have these growth factors implanted at their injury site along with standard rehabilitation t…

This study tests whether an AI-powered mobile app can help people with spinal cord injury manage bowel problems better. About 34 adults will use the app to learn bowel care routines. The goal is to reduce bowel dysfunction scores, shorten bathroom time, and improve quality of lif…

This study tests whether adding a gentle electrical stimulation to the spinal cord during walking therapy can help people with a recent spinal cord injury (within the last 6 months) regain more leg movement. Forty participants will either receive walking therapy alone or walking …

This study tests a live, group tele-exercise program (TEEMS) for 200 adults with spinal cord injury. Participants will join online classes or watch pre-recorded videos for 8 weeks. The goal is to see if the live program improves exercise confidence, physical activity, and quality…

This study tests an online program called EmpowerSpine for people with spinal cord injury who have chronic pain. The program teaches pain biology, daily coping strategies, and resilience skills. Researchers will test which parts of the program—like coach guidance, peer support, o…

This study looks at whether a type of talk therapy called Focused Acceptance and Commitment Therapy (FACT) can help people with a spinal cord injury feel better mentally and improve their quality of life. About 8 people recovering in the hospital will try FACT and fill out questi…

This study tests if a special arm-crank exercise (eccentric training) is better than usual strength training for people recovering from a spinal cord injury. Twenty adults in early rehab will do 20 sessions over 12 weeks. Researchers will measure changes in upper body strength, f…

This study tests whether a home-based digital rehabilitation program combined with a non-invasive spinal stimulation device can safely improve arm and hand function in people with chronic tetraplegia. Nine adults with spinal cord injury will use a mobile app-guided exercise progr…

This study tests a new AI system that automatically adjusts electrical stimulation to the spinal cord in real time while people walk. The goal is to improve muscle activation and walking ability in people with incomplete spinal cord injury. The study will compare this smart stimu…

This study checks if a short questionnaire about bladder symptoms works well in Turkish for adults with spinal cord injury or multiple sclerosis. Researchers will ask 120 people to fill out the form and compare it with other surveys to ensure it is accurate and reliable. The goal…

This study aims to improve a mobile brain-computer interface (BCI) that lets people with paralysis control computers and mobile devices using only their thoughts. Researchers will test the system's accuracy and ease of use in 2 participants who are already enrolled in a separate …

This study looks back at medical records of 50 people with spinal cord injuries to learn about their age, gender, injury causes, and complications like pressure sores or infections. The goal is to better understand these injuries and improve future care. No new treatments are giv…

This study tests a program that gives veterans with spinal cord injury and bladder issues the tools to talk to their doctors and avoid antibiotics they may not need. The goal is to reduce antibiotic resistance, a serious public health problem. About 30 veterans will take part to …

This study looks at whether a simple home-based shoulder exercise program can improve shoulder health in manual wheelchair users with spinal cord injury. Forty participants will start training either 3 or 12 months after leaving rehab, doing exercises twice a week for 12 weeks. R…

This study follows 16 people who already received EG110A, a gene therapy for overactive bladder caused by spinal cord injury. Researchers will track side effects and how well the treatment works over five years. The goal is to understand long-term safety and dosing.

This study looks at how the Achilles tendon behaves during walking in people with spastic paresis (muscle stiffness) caused by stroke or spinal cord injury. Researchers will measure tendon stiffness, length, and volume, as well as calf muscle strength, using ultrasound and force …