SPINAL CORD INJURY

This study tested whether a daily injection (teriparatide) and/or daily vibration therapy could help rebuild bone in people with long-term spinal cord injuries who cannot walk. Sixty participants were assigned to receive either the drug, the vibration, both, or neither for one ye…

This study tested whether repeated sessions of passive heating (like using a heating pad or warm water) could help improve health for people with spinal cord injuries. People with these injuries have a higher risk of heart disease and diabetes, partly due to chronic inflammation.…

This study tested a new rehabilitation approach for people with spinal cord injuries. It combined two technologies: an implanted device that electrically stimulates the spinal cord and a wearable robotic exoskeleton that helps with walking. The goal was to see if using them toget…

This VA study tested whether gentle electrical stimulation through the skin could help stabilize blood pressure in veterans with spinal cord injuries. Researchers worked with 10 participants to find the best placement and settings for electrodes on the back. The goal was to devel…

This study tested whether keeping a patient's blood pressure at a higher target range in the first week after a spinal cord injury leads to better recovery. Researchers compared two different blood pressure targets to see which one improved patients' movement, sensation, pain, an…

This study tested whether a medication called zoledronic acid could prevent the severe bone loss that often happens after a spinal cord injury. For two years, researchers compared the drug to a placebo in 60 adults who had a recent injury and could not walk independently. The goa…

This early study tested whether surgically implanting a biodegradable device containing growth factors into the spinal cord could help restore function in people with complete spinal cord injuries. Ten participants with injuries between the chest and lower back were randomly assi…

This study tested whether an experimental drug called MT-3921 could help improve arm and hand function in people who had recently suffered a severe spinal cord injury in their neck. 72 participants were randomly assigned to receive either the drug or a placebo (inactive substance…

This study tested a new combination treatment to rebuild leg muscles in people with spinal cord injury who have severe nerve damage. Researchers gave participants testosterone and used a special type of electrical stimulation designed to work on muscles that don't respond to stan…

This study tested a home-based program combining electrical muscle stimulation and vitamin D supplements to see if it could improve bone health in Veterans with long-term spinal cord injuries. The goal was to find a way to slow or reverse severe bone loss, which is a common and s…

This study tested two community-based wellness programs to see if they could improve health, increase life satisfaction, and reduce healthcare costs for adults with disabilities like cerebral palsy or spinal cord injury. It involved 130 participants who were eligible for specific…

This study tested whether an 8-week, high-intensity exercise program could improve mobility in daily life for people with neurologic disabilities like stroke, cerebral palsy, or spinal cord injury. Fifteen participants aged 8-99 took part in the program, which was run by physical…

This small study tested whether a combined treatment is practical for people with chronic nerve pain after a spinal cord injury. Four participants tried a two-week program of virtual walking and a gentle, non-invasive brain stimulation technique. The main goal was to see if patie…

This study tested whether daily electrical stimulation could help rebuild muscle and improve sitting comfort for people with long-term spinal cord injuries. Thirty participants used a stimulator on their buttock muscles for 35 minutes daily over six months. Researchers measured c…

This study tested whether a single dose of an experimental drug called KAI-1678 could reduce pain in people with long-term spinal cord injuries. Five participants received either the drug or a placebo in a random order to see which worked better. The main goal was to see if the d…

This study tested whether dextromethorphan, an ingredient found in some cough medicines, could reduce chronic nerve pain in people with spinal cord injuries. Twenty-six adults with this type of pain tried different doses of the drug and a placebo to see which worked best. The goa…

This study tested different combinations of two existing medications (dextromethorphan and lidocaine) to see which mix best reduced chronic nerve pain in people with spinal cord injuries. Twenty-six participants tried different dose combinations in a carefully controlled trial to…

This small study tested whether an 8-week online group support program is practical and helpful for people living with a spinal cord injury. Twelve participants in Hong Kong attended weekly video meetings led by a trained nurse to learn coping skills. The main goal was to see if …

This study used MRI brain scans to understand how spinal cord injury affects thinking skills like focus, word recall, and mental flexibility. Researchers compared brain activity and structure in 54 adults with and without spinal cord injury while they performed thinking tasks. Th…

This study aimed to understand how people with spinal cord injuries recover walking ability during robot-assisted therapy. Ten participants completed 40 sessions of gait training with a robotic device called the Lokomat. Researchers closely measured their progress through clinica…

This study aimed to learn about the experiences of women with spinal cord injury regarding having children, using birth control, and pregnancy. Researchers surveyed 70 women aged 18-55 who had been living with their injury for over a year. The goal was to gather information to be…

This study measured how a robotic body-weight support system called the FLOAT affects movement during daily activities like walking, standing, and climbing stairs. Researchers compared movements with and without the robotic assistance in 60 people with incomplete spinal cord inju…

This study aimed to discover molecules in the blood, urine, and stool that are linked to better recovery after a spinal cord injury. Researchers followed 106 people (66 with recent injuries and 40 without) for a year, collecting samples and tracking their physical function. The g…

This research study aimed to understand how the brain communicates with muscles after a spinal cord injury. Researchers measured brain signals and muscle responses during reaching and grasping movements in 120 people with and without spinal cord injuries. The goal was to gather i…

This study looked at whether a simple ultrasound scan of the bladder wall could provide similar information to more invasive urodynamic tests in people with spinal cord injury. Researchers measured the bladder thickness of 116 participants using an external ultrasound and compare…