SPINAL CORD INJURY

This study tested a new rehab approach for people with spinal cord injury. Ten participants used a device that sends electrical pulses to the spinal cord while wearing a robotic exoskeleton to help them walk. The goal was to improve leg strength and movement. While not a cure, th…

This study tested a biodegradable device that releases growth factors to help damaged nerves regrow in people with complete spinal cord injury. Ten participants received either the implant plus rehabilitation or rehabilitation alone. The goal was to see if the implant is safe and…

This study tested an experimental drug called MT-3921 in 72 people with recent cervical spinal cord injuries. Participants received either the drug or a placebo over 6 months. The main goal was to see if the drug improves arm and hand movement, measured by a standard motor score.…

This study tested whether repeated sessions of passive heating (like sitting in a warm room or bath) three times a week for eight weeks could reduce inflammation and improve heart and blood vessel health in people with spinal cord injury. Ten adults with stable spinal cord injury…

This pilot study tested whether combining electrical muscle stimulation with vitamin D supplements could improve bone health in veterans with chronic spinal cord injury. Six participants received the treatment over 9 months, and researchers measured changes in bone structure usin…

This study tested whether a bone-building drug (teriparatide) and whole-body vibration, alone or together, can increase bone density in people with chronic spinal cord injury. 60 adults with low bone mass took part over 12 months. The goal was to see if these treatments could slo…

This study tested a new approach for people with spinal cord injury whose leg muscles have shrunk because the nerves are damaged. Researchers combined testosterone therapy with a special type of electrical stimulation to try to rebuild muscle size and improve health. The 12 parti…

This study looked at whether a single dose of zoledronic acid, a drug already used for osteoporosis, could prevent the rapid bone loss that often happens after a spinal cord injury. Researchers followed 60 adults who had recently been injured and could not walk independently. The…

This study tested three doses of dextromethorphan, a common cough medicine, against a placebo to see if it could reduce nerve pain in people with spinal cord injuries. 26 adults with chronic central neuropathic pain took part. The goal was to measure changes in pain intensity and…

This study tested whether a drug called KAI-1678 can reduce pain in people with spinal cord injury. Five adults with long-term spinal cord injury and ongoing nerve pain received either the drug or a placebo. The goal was to see if the drug lowered pain intensity within 6 hours.

This study tested whether a high-intensity exercise program, run by physical therapy students, helps people with neurologic disabilities move better in everyday life. Fifteen participants with conditions like cerebral palsy, stroke, or spinal cord injury completed the program. Th…

This study tested a 7-week program that teaches people with spinal cord injury how to manage their chronic pain using brain-based education, coaching, and tools like movement and massage. Twelve adults in Canada took part in group sessions and one-on-one coaching to learn pain se…

This study tested whether daily electrical stimulation of the buttock muscles for 35 minutes over six months could increase muscle size and improve pressure distribution while sitting in people with chronic spinal cord injury. Thirty participants with long-term spinal cord injury…

This small study tested whether combining virtual walking (a computer simulation) with a gentle brain stimulation technique (tDCS) could help ease chronic nerve pain in people with spinal cord injury. Four participants tried the treatment for two weeks, keeping diaries and answer…

This small pilot study tested two ways to stimulate the spinal cord (surface or implanted) combined with a robotic exoskeleton to help people with spinal cord injury walk. Four men with complete motor paralysis below the chest took part. The goal was to see if these approaches im…

This study tested a non-invasive method using mild electrical stimulation on the skin over the spine to help raise and stabilize blood pressure in 10 veterans with spinal cord injury who had chronically low blood pressure. The goal was to find the best placement and settings for …

This study tested a new online program called E-COSP designed to help people with spinal cord injury cope better and improve their mental health. Twelve adults with spinal cord injury who had mild to moderate anxiety or depression took part in eight weekly online group sessions l…

This study tested simple, low-cost devices to help people with spinal cord injury practice walking on a treadmill. Nineteen adults with spinal cord injury took part. The goal was to see if the devices could improve walking speed and leg movement.

This study tested whether a combination of two drugs, dextromethorphan and lidocaine, can reduce nerve pain in people with spinal cord injuries. 26 adults received different doses of the drugs or a placebo to see which worked best. The goal was to find a better way to ease this t…

This study looked at how spinal cord injury might affect thinking skills like focus and word recall. Researchers used MRI scans to measure brain activity in 54 adults with and without spinal cord injury during thinking tasks. The goal was to better understand these hidden challen…

This study looked at 94 adults with a recent spinal cord injury to see if keeping blood pressure at a higher or lower target for the first week helps recovery. Participants were split into two groups: one with a standard blood pressure goal and one with a higher goal. Researchers…

This study tested a new robotic device called REACTION that helps with walking and balance in people with stroke or spinal cord injury. Seven participants tried the device in two sessions, doing walking and balance tasks, and then gave feedback in an interview. The goal was to se…

This study looked at how the brain sends signals to muscles after a spinal cord injury. Researchers tested 120 people with chronic neck-level injuries to understand how these signals work and how to improve hand and arm movement. The goal is to develop better therapies to help pe…

This study looked at how a robotic body-weight support system called 'the FLOAT' changes the way people with incomplete spinal cord injury perform everyday tasks like walking, standing up, and climbing stairs. About 65 participants (including healthy volunteers) did these activit…

This study looked at how robot-assisted walking training helps people with spinal cord injuries recover movement. Ten participants used a robotic device called Lokomat to practice walking. Researchers measured their progress before, during, and after training, and one month later…

This study analyzed blood and other samples from 106 adults with recent spinal cord injuries to find molecules linked to better recovery. Researchers tracked patients before and after rehabilitation and one year later. The goal was to identify biological clues that could one day …

This study looked at how spinal cord injury affects women's experiences with fertility, birth control, and pregnancy. Researchers surveyed 70 women aged 18-55 who had been injured for more than a year. The goal was to understand their needs and challenges, not to test a treatment…

This study looked at whether measuring bladder wall thickness with an ultrasound can give useful information about bladder function in people with spinal cord injury. Researchers compared ultrasound measurements with detailed bladder tests in 116 adults. The goal was to see if a …

This study tested two community-based wellness programs for 130 adults with disabilities such as spina bifida, cerebral palsy, spinal cord injury, or traumatic brain injury. Researchers measured changes in health, mood, quality of life, and healthcare costs over up to 24 months. …