New drug tested to help regain arm and hand movement after spinal injury

NCT ID NCT04683848

Summary

This study tested whether an experimental drug called MT-3921 could help improve arm and hand function in people who had recently suffered a severe spinal cord injury in their neck. 72 participants were randomly assigned to receive either the drug or a placebo (inactive substance) through an IV over 6 months. The main goal was to see if the drug was safe and if it led to better scores on tests measuring muscle strength and the ability to perform daily tasks.

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Contacts and locations

Locations

  • Augusta University

    Augusta, Georgia, 30912, United States

  • Brooke Army Medical Center in San Antonio

    Houston, Texas, 78234, United States

  • Carilion Clinic

    Roanoke, Virginia, 24014, United States

  • Carolinas Rehabilitation

    Charlotte, North Carolina, 28203, United States

  • Gifu University Hospital

    Gifu, Gifu, 501-1194, Japan

  • Hokkaido Spinal Cord Injury Center

    Bibai-shi, Hokkaido, 072-0015, Japan

  • Japan Organization of Occupational Health and Safety SPINAL INJURIES CENTER

    Izuka-shi, Fukuoka, 820-8508, Japan

  • Japanese Red Cross Kobe Hospital

    Kobe, Hyōgo, 651-0073, Japan

  • Medical College of Wisconsin - Froedtert Hospital

    Milwaukee, Wisconsin, 53226, United States

  • Murayama Medical Center

    Musashimurayama-shi, Tokyo, 208-0011, Japan

  • NSHA-Queen Elizabeth II Health Sciences Centre

    Halifax, Nova Scotia, B3H3A7, Canada

  • National Hospital Organization Kumamoto Medical Center

    Kumamoto, Kumamoto, 860-0008, Japan

  • Oregon Health and Science University - Center for Health & Healing

    Portland, Oregon, 97239, United States

  • Saint Louis University Hospital

    St Louis, Missouri, 63110, United States

  • Spectrum Health

    Grand Rapids, Michigan, 49503, United States

  • Tallahassee Neurological Clinic

    Tallahassee, Florida, 32308, United States

  • The Ottawa Hospital

    Ottawa, Ontario, K1Y4E9, Canada

  • The University of Texas Health Science Center at San Antonio

    San Antonio, Texas, 78229, United States

  • University of California Irvine

    Orange, California, 92868, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45219, United States

  • University of Kentucky

    Lexington, Kentucky, 40536, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.