RETINITIS PIGMENTOSA

This large, late-stage trial is testing whether a common antioxidant pill called N-acetylcysteine (NAC) can slow the progression of retinitis pigmentosa, an inherited eye disease that causes gradual vision loss. About 485 adults with the condition will take either NAC or a placeb…

This study is checking the long-term safety and side effects of a high-dose antioxidant supplement called N-Acetylcysteine (NAC) in 30 adults with retinitis pigmentosa, a disease that damages vision. The goal is to see if people can safely take this medication twice daily for an …

This is the first-ever human study of an experimental gene therapy called CPK850 for a rare, inherited form of vision loss called RLBP1 retinitis pigmentosa. The main goals are to find a safe dose and see if a single injection into the eye can help improve patients' vision, espec…

This early-stage study is checking if it's safe and possible to treat vision loss by injecting a patient's own bone marrow stem cells directly into the eye. It involves 15 adults who have lost vision from conditions like macular degeneration or diabetic retinopathy. The main goal…

This is an early safety study testing a single injection of an experimental gene therapy called RTx-015 into the eye. It aims to see if the treatment is safe for adults with retinitis pigmentosa or choroideremia, two inherited diseases that cause vision loss. Researchers will giv…

This Phase 3 study is testing whether a one-time gene therapy called OCU400 can help preserve functional vision in people with retinitis pigmentosa (RP), a genetic disease that causes progressive vision loss. The therapy is injected under the retina. The study has enrolled 140 pa…

This study is testing whether a gentle electrical current applied to the eye can help preserve or improve vision in people with retinitis pigmentosa, a genetic eye disease that causes progressive vision loss. Researchers are measuring changes in visual field, sharpness, and contr…

This study aims to understand how quickly vision declines in people with a specific genetic cause of Usher syndrome, a condition that causes both hearing and vision loss. Researchers will follow 44 participants with PCDH15 gene mutations for four years, measuring their vision and…

This study aims to understand how vision declines in people with severe retinitis pigmentosa, a rare genetic eye disease. Researchers will follow 12 adults for one year to identify which vision tests work best for tracking disease progression. The study doesn't test treatments bu…

This study aims to understand how vision changes over time in adults with a specific genetic form of retinitis pigmentosa (caused by EYS gene mutations). Researchers will observe 103 participants for four years, measuring their vision and eye structure in detail. The goal is to g…