Gene therapy trial aims to restore night vision in rare eye disease
NCT ID NCT06388200
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a gene therapy called OCU400 for people with retinitis pigmentosa, an inherited eye disease that causes vision loss. The treatment is injected under the retina to help light-sensitive cells work better. The trial enrolled 140 people aged 3 and older and measures if they can navigate a maze in dim light after one year.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advanced Research, LLC.
Deerfield Beach, Florida, 33064, United States
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Associated Retina Consultants
Phoenix, Arizona, 85020, United States
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Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine
Miami, Florida, 33136, United States
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Calgary Retina Consultants
Calgary, Alberta, T2H OC8, Canada
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Erie Retina Research LLC
Erie, Pennsylvania, 16507, United States
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Gundersen Health System
La Crosse, Wisconsin, 54601, United States
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Research Institute of the McGill University Health Centre
Montreal, Quebec, H2W 1L4, Canada
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Retina Consultants of Texas
Bellaire, Texas, 77401, United States
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Retina Foundation of the Southwest
Dallas, Texas, 75231, United States
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Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5, Canada
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The University of British Columbia
Vancouver, British Columbia, V5Z 3N9, Canada
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University of Alberta
Edmonton, Alberta, T6G 3E1, Canada
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University of Southern Califormia
La Jolla, California, 92093, United States
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University of Southern California, Roski Eye Insitute
Los Angeles, California, 90033, United States
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Valley Retina Institute
McAllen, Texas, 78503, United States
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Vanderbilt Eye Institute
Nashville, Tennessee, 37232, United States