Vision loss study paves way for future treatments

NCT ID NCT04765345

First seen Feb 03, 2026 · Last updated May 01, 2026 · Updated 12 times

Summary

This study follows 44 people with a rare genetic eye condition (PCDH15-related Usher syndrome) over 4 years to measure how their vision changes. No treatment is given. The goal is to understand the disease's natural course so that future clinical trials can test new therapies more effectively.

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Contacts and locations

Locations

  • CHNO des Quinze-Vingts

    Paris, France

  • Duke University, Duke Eye Center

    Durham, North Carolina, 27710, United States

  • Haddassah Medical Center

    Jerusalem, Israel

  • Hospital for Sick Children

    Toronto, Ontario, Canada

  • Moorfields Eye Hospital

    London, EC1V 2PD, United Kingdom

  • Radboud University

    Nijmegen, Netherlands

  • The Johns Hopkins Wilmer Eye Institute

    Baltimore, Maryland, 21287, United States

  • University Hospital Basel

    Basel, 4031, Switzerland

  • University of California, San Francisco

    San Francisco, California, 94143-0344, United States

  • University of Tubingen

    Tübingen, Germany

Conditions

Explore the condition pages connected to this study.