Autosomal recessive nonsyndromic hearing loss 23
MONDO:0012293Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the PCDH15 gene.
Also known as: DFNB23, PCDH15 autosomal recessive nonsyndromic deafness, autosomal recessive deafness 23, autosomal recessive nonsyndromic deafness 23, autosomal recessive nonsyndromic deafness caused by mutation in PCDH15, autosomal recessive nonsyndromic deafness type 23, deafness, autosomal recessive 23, deafness, autosomal recessive type 23
61 clinical trials for this condition and its sub-types.
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Cochlear implant electrode gets a new spot near the vagus nerve
Disease control Recruiting nowThis study tests whether placing a cochlear implant's ground electrode near the vagus nerve behind the ear works as well as the standard placement under a muscle. Twelve adults getting a cochlear implant will participate. The main goal is to see if speech understanding in noise i…
Phase: NA • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Brainstem implant offers hope for children born without hearing nerves
Disease control Recruiting nowThis study tests an auditory brainstem implant in 20 children who are deaf because they are missing the inner ear or the nerve that carries sound to the brain. The device is surgically placed to stimulate the brainstem directly, bypassing the missing parts. Researchers will monit…
Phase: NA • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Which hearing test works best for preschoolers? major study aims to find out
Diagnosis Recruiting nowThis study compares two common hearing screening methods—pure-tone audiometry and otoacoustic emissions—in over 13,000 preschool children. The goal is to determine which method is better at identifying hearing loss early, so children can get the help they need to avoid speech and…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Diagnosis
Last updated Jun 27, 2026 09:01 UTC
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Simple tweak to cochlear implant settings could improve sound quality
Symptom relief Recruiting nowThis study is testing whether changing the frequency settings on a cochlear implant can improve sound quality and speech understanding for people who use both a cochlear implant and a hearing aid. Thirteen experienced bimodal users will try an experimental frequency setting for o…
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC
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New hearing aid tech aims to unmuffle whispered conversations
Symptom relief Recruiting nowThis study tests a new way for hearing aids to process soft sounds, aiming to make quiet speech clearer. Sixteen adults with hearing loss will try two different hearing aid settings in a lab and rate which one sounds more natural and understandable. The goal is to improve hearing…
Phase: NA • Sponsor: Sebastian Griepentrog • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can smart cochlear implants help kids hear better in noise?
Symptom relief Recruiting nowThis study tests whether automatic sound processing in cochlear implants helps children with hearing loss understand speech in noisy environments. Twenty children aged 6 to 16 who use cochlear implants will compare three different sound settings. The goal is to see which setting …
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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AI hearing aids aim to cut through the chatter
Symptom relief Recruiting nowThis study tests whether a new AI-based noise reduction feature in Phonak hearing aids helps people with hearing loss or cochlear implants hear speech more clearly in noisy settings. Researchers will measure how well 500 participants repeat words and sentences in quiet and noisy …
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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New algorithm aims to help cochlear implant users hear in noise
Symptom relief Recruiting nowThis study is testing a new software algorithm called SEDA that reduces background noise for cochlear implant users. Researchers will measure how well 60 participants (ages 12 and older) understand speech in quiet and noisy settings with and without the algorithm. The goal is to …
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New hearing aid aims to boost sound for millions
Symptom relief Recruiting nowThis study tests a new hearing aid, Audiocap, in 100 adults with mild-to-moderate hearing loss who have never used a hearing aid before. The goal is to see if it improves hearing better than a placebo device after one month of use. Participants will undergo standard hearing tests…
Phase: NA • Sponsor: Archean Technologies • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Virtual reality eyewear tested to soothe dental fears in children with hearing loss
Symptom relief Recruiting nowThis study compares using virtual reality glasses versus the standard 'show-do' technique to reduce dental anxiety in 54 children with moderate to severe hearing impairment. The children will have their pulse and anxiety scores measured during a dental cleaning. The goal is to se…
Phase: NA • Sponsor: October University for Modern Sciences and Arts • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Smartphone hearing aid fits by community workers could transform ear care
Symptom relief Recruiting nowThis study tests whether community healthcare workers can effectively fit hearing aids using a smartphone app in low- and middle-income communities. 90 adults with mild to severe hearing loss will be randomly assigned to receive either a smartphone-based fitting, a pre-set fittin…
Phase: NA • Sponsor: University of Pretoria • Aim: Symptom relief
Last updated Jun 26, 2026 14:04 UTC
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Massive study to track how hearing treatments shape Kids' brains
Knowledge-focused Recruiting nowThis study will follow 5,000 children and teens with hearing loss and normal hearing over time. Researchers will measure changes in hearing, speech, language, and brain scans to see how different treatments—like hearing aids, cochlear implants, or gene therapy—affect development.…
Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Scientists uncover how hearing loss affects speech recognition in noisy environments
Knowledge-focused Recruiting nowThis study looks at how people with normal hearing, hearing loss, or cochlear implants use nearby sounds to recognize speech. Researchers will test participants' ability to identify words and sentences in quiet and noisy settings. The goal is to better understand how hearing aids…
Phase: NA • Sponsor: Marquette University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New program aims to bridge hearing care gap in rural kentucky
Knowledge-focused Recruiting nowThis study tests a patient navigation program to help rural adults in Kentucky get hearing tests. 500 participants from primary care clinics will receive guidance every two weeks to overcome barriers like travel and cost. The goal is to see if more people complete diagnostic hear…
Phase: NA • Sponsor: Matthew Bush, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Hearing aid study aims to unlock secrets of sound perception
Knowledge-focused Recruiting nowThis study looks at how people with hearing aids perceive the timbre (quality) of sounds and understand complex sound scenes, like music or crowded rooms. Researchers will compare 75 adults aged 60-75 with and without hearing loss. Participants will listen to sounds and rate how …
Phase: NA • Sponsor: Institut Pasteur • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Can new sound coding unlock better hearing for kids with cochlear implants?
Knowledge-focused Recruiting nowThis study aims to improve how children with cochlear implants perceive sound by testing new sound coding strategies. Researchers will compare hearing performance between children and adults, and between those with implants and those with normal hearing. The goal is to understand…
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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New study seeks to unlock the hidden struggles of deaf teens
Knowledge-focused Recruiting nowThis nationwide study aims to understand how hearing loss affects thinking, language, reading, and emotional wellbeing in 256 deaf or hard-of-hearing adolescents. Researchers will use tests and questionnaires to measure speech perception, cognitive skills, and school burnout. No …
Sponsor: Heikki Löppönen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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New study tracks Real-World hearing device outcomes
Knowledge-focused Recruiting nowThis study is gathering information from 100 children and adults who use MED-EL hearing devices, including implants and non-implantable devices. Researchers will collect data on hearing ability, speech understanding, and quality of life through tests and questionnaires. The goal …
Sponsor: MED-EL Elektromedizinische Geräte GesmbH • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Scientists investigate how hearing implants help the deaf perceive sound
Knowledge-focused Recruiting nowThis research study looks at how children and adults who use cochlear implants or auditory brainstem implants hear and understand sounds. Participants will listen to words, sentences, and tones to see how well they identify speech and tell differences in loudness or pitch. The go…
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Balance trouble linked to reading struggles in kids with hearing loss
Knowledge-focused Recruiting nowThis study looks at whether inner-ear balance (vestibular) problems make reading harder for children with hearing loss. Researchers will test 90 children, some with normal hearing and some with severe hearing loss, measuring their ability to see clearly during head movements and …
Phase: NA • Sponsor: Father Flanagan's Boys' Home • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Cochlear implant Users' listening effort under the microscope
Knowledge-focused Recruiting nowThis study looks at how people with cochlear implants understand speech in everyday situations, like conversations with background noise. Researchers will test 460 adults (both with and without hearing loss) using listening tasks that measure effort and comprehension. The goal is…
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC