Alga supplement could boost sight in rare eye disease

NCT ID NCT07509229

ENROLLING_BY_INVITATION Disease control Sponsor: Sheba Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 28, 2026 · Updated 3 times

Summary

This study tests whether a natural supplement from Dunaliella alga, rich in 9-cis beta-carotene, can improve vision in adults with retinitis pigmentosa. Forty-one participants will take the supplement or a placebo for 3 months, then switch after a 6-month break. Researchers will measure retinal sensitivity, electrical responses, and blood levels of vitamin A.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 9-cis beta-carotene-rich extract of Dunaliella alga (dietary supplement)
What this could lead to: If it works, this could point toward a natural supplement that slows vision loss or improves light sensitivity in retinitis pigmentosa.
What could go wrong: This is an early Phase 1/2 trial with only 41 people, so results may not apply broadly. The supplement may not improve vision and could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

retinitis pigmentosa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RETINITIS PIGMENTOSA

Contacts and locations

Locations

Goldschleger Eye Institute, Sheba Medical Center,

Tel Litwinsky, 52621, Israel

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