Sheba Medical Center

This study tests whether adding azithromycin to the usual antibiotic (ampicillin) can reduce serious health problems in newborns when a pregnant person's water breaks early (between 34 and 37 weeks). About 311 participants will receive either ampicillin alone or ampicillin plus a…

This study follows 120 children and teens with type 1 diabetes who are using the Medtronic 780G system, a closed-loop insulin pump that automatically adjusts insulin. Researchers want to see if the system improves blood sugar control and quality of life over two years. Participan…

This study tests a new treatment for people with certain blood cancers (B-cell malignancies) that have come back or not responded to standard therapies. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack cancer cells carrying a …

This study is testing whether a portable virtual reality (VR) headset can help diagnose and monitor traumatic brain injury (TBI), like concussions. The device shines colored lights into the eyes and uses a camera to measure how the pupils react. Researchers will compare results f…

This study tests if the drug carbetocin works better than standard oxytocin to prevent heavy bleeding after delivering twins. Heavy bleeding is more common with twin births and can cause serious health problems. About 120 pregnant women with twins will be randomly assigned to rec…

This study compares group-based MDMA-assisted therapy to individual sessions for people diagnosed with PTSD after the events of October 7, 2023. Researchers want to see if group therapy is as safe and effective as individual therapy. 168 adults will receive MDMA along with talk t…

This study is testing a new, non-invasive eye test called pupillometry to see if it can detect vision problems in people with pseudotumor cerebri (a condition where pressure builds up in the brain). Researchers will compare the pupil responses of 100 participants (patients and he…

This study looks at whether people with Oculopharyngeal Muscular Dystrophy (OPMD) have thicker saliva and worse oral health compared to healthy individuals. Researchers will collect saliva samples and check mouth health in 100 participants, including patients and their household …

This study looks at whether the way you hold your arm during a blood pressure check changes the reading in pregnant women. About 300 pregnant women will have their blood pressure taken with their arm in different positions—supported at heart level, on their lap, or hanging at the…

This study looks at how laser light bounces off different parts of the eye, like the cornea and retina. The goal is to make eye exams and laser treatments safer. Twenty healthy volunteers aged 18 to 40 will have their eyes tested with low-level lasers at different angles and colo…

This study explores whether briefly opening the blood-brain barrier during spine surgery can release brain tumor markers into the blood, making them easier to detect with a simple blood test. About 20 adults having spine surgery for spinal tumors will take part. Researchers will …