Cure My Disease

Don't miss your cure!

 Log in / Sign up

Muscle-Saving combo: exercise and diet may counteract Semaglutide-Related muscle loss in seniors

NCT ID NCT06497595

Recruiting now Disease control Sponsor: Sheba Medical Center Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether a structured exercise and nutrition program can slow the loss of muscle mass, strength, and function in adults aged 65 and older with type 2 diabetes and obesity who are taking semaglutide. Participants receive either standard health advice or a 26-week program including online exercise sessions and personal dietary counseling. The goal is to see if these lifestyle changes can help preserve physical ability while managing weight and blood sugar.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
semaglutide (Wegovy) plus a 26-week exercise and nutritional counseling program
What this could lead to
If successful, this approach could help older adults on semaglutide preserve muscle strength and function, reducing frailty and fall risk.
What could go wrong
This is a small, early-stage trial with 60 participants, so results may not apply broadly. The exercise and diet program requires high adherence, which can be challenging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBESITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Motor Activity Obesity obesity disorder Sarcopenia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES MELLITUS IN OBESE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hadassah Medical Center

    NOT_YET_RECRUITING

    Jerusalem, Israel, 5251108, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sheba medical center

    RECRUITING

    Ramat Gan, Israel, 52621, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.