Sheba Medical Center
Clinical trials sponsored by Sheba Medical Center, explained in plain language.
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New CAR-T therapy aims to tackle tough blood cancers
Disease control Not yet recruitingThis trial tests a new treatment called SHB-02-CD19, which uses a patient's own immune cells engineered to attack cancer cells that have a protein called CD19. It is for children and adults with B-cell cancers (like leukemia or lymphoma) that have come back or not responded to at…
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Could fewer infusions tame thyroid eye disease?
Disease control Not yet recruitingThis study compares a shortened 4-infusion course of the drug Teprotumumab (Tepezza) against the standard 8-infusion course for people with active thyroid eye disease. Only patients who show a good early response will be eligible for the shorter regimen. The goal is to see if few…
Phase: PHASE4 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Could pond scum help teens see better? new trial tests alga extract for rare eye disease
Disease control Not yet recruitingThis study tests whether a powder made from a special alga can help preserve or improve vision in teenagers with retinitis pigmentosa, a genetic eye disease that causes vision loss. Thirty participants aged 12-18 will take the alga extract daily for one year. The study will measu…
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Can silicone sheets boost scar healing beyond pressure garments alone?
Symptom relief Not yet recruitingThis trial asks whether combining silicone sheets with standard pressure garments can improve the appearance and quality of limb scars better than pressure garments alone. About 60 adults aged 18-65 with scars from injury or surgery will receive either the combined treatment or p…
Phase: NA • Sponsor: Sheba Medical Center • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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No-Needle patch could protect your smile during surgery
Knowledge-focused Not yet recruitingThis study tests a wireless patch that sticks to the face to monitor facial nerves during surgery, aiming to prevent nerve damage. It will be used alongside standard needle-based monitoring in 20 adults having parotid or facial surgery. Researchers will compare how well the patch…
Phase: NA • Sponsor: Sheba Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Blood cell energy study could predict ketamine response in depression
Knowledge-focused Not yet recruitingThis study looks at how S-ketamine, a treatment for severe depression, affects tiny energy centers (mitochondria) in blood cells. Researchers will take blood samples from 30 adults with treatment-resistant depression before and after treatment. They hope to find markers that pred…
Sponsor: Sheba Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC