Sheba Medical Center

This study tests whether a natural supplement from Dunaliella alga, rich in 9-cis beta-carotene, can improve vision in adults with retinitis pigmentosa. Forty-one participants will take the supplement or a placebo for 3 months, then switch after a 6-month break. Researchers will …

This trial tests a new treatment called SHB-02-CD19, which uses a patient's own immune cells engineered to attack cancer cells that have a protein called CD19. It is for children and adults with B-cell cancers (like leukemia or lymphoma) that have come back or not responded to at…

This study compares a shortened 4-infusion course of the drug Teprotumumab (Tepezza) against the standard 8-infusion course for people with active thyroid eye disease. Only patients who show a good early response will be eligible for the shorter regimen. The goal is to see if few…

This study tests whether a powder made from a special alga can help preserve or improve vision in teenagers with retinitis pigmentosa, a genetic eye disease that causes vision loss. Thirty participants aged 12-18 will take the alga extract daily for one year. The study will measu…

This study tests a wireless patch that sticks to the face to monitor facial nerves during surgery, aiming to prevent nerve damage. It will be used alongside standard needle-based monitoring in 20 adults having parotid or facial surgery. Researchers will compare how well the patch…

This study looks at how S-ketamine, a treatment for severe depression, affects tiny energy centers (mitochondria) in blood cells. Researchers will take blood samples from 30 adults with treatment-resistant depression before and after treatment. They hope to find markers that pred…