Sheba Medical Center
Clinical trials sponsored by Sheba Medical Center, explained in plain language.
-
Can pond algae help teens see better? new trial aims to slow vision loss
Disease control Not yet recruitingThis study tests whether a powder made from a special alga can improve vision in 30 teenagers with retinitis pigmentosa, a genetic eye disease that causes vision loss. Participants will take the alga extract daily for a year while doctors measure changes in their eye function. Th…
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated May 17, 2026 12:02 UTC
-
Could fewer infusions be enough for thyroid eye disease?
Disease control Not yet recruitingThis study compares a shortened 4-infusion course of the drug Teprotumumab (Tepezza) to the standard 8-infusion course in people with active thyroid eye disease. It aims to see if those who respond well early can safely stop treatment sooner. About 40 participants who show early …
Phase: PHASE4 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated May 17, 2026 11:57 UTC
-
New CAR T-Cell therapy targets Hard-to-Treat blood cancers
Disease control Not yet recruitingThis study tests a new treatment called SHB-02-CD19 for people with certain blood cancers (B-cell malignancies) that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to recognize and attack cancer cells. The goal is …
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
-
Algae extract may slow vision loss in rare eye disease
Disease control Not yet recruitingThis study tests whether a natural supplement made from algae can improve vision in adults with Retinitis Pigmentosa, an inherited eye disease that causes gradual vision loss. Forty-one participants will take either the supplement or a placebo for 3 months, then switch after a 6-…
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
-
Sticky patch could replace needles in facial surgery monitoring
Knowledge-focused Not yet recruitingThis study tests a non-invasive wireless patch that monitors facial nerve activity during parotid or facial surgery, aiming to see if it works as well as the standard needle-based method. Twenty adults will have both monitoring methods used during their surgery, and researchers w…
Phase: NA • Sponsor: Sheba Medical Center • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC
-
Scientists probe cell power plants to predict depression treatment success
Knowledge-focused Not yet recruitingThis study looks at whether S-ketamine changes the function of mitochondria (the energy centers of cells) in people with treatment-resistant depression. Researchers will take blood samples from 30 adults before, shortly after, and six weeks after treatment to see if these changes…
Sponsor: Sheba Medical Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC