Blood test breakthrough? opening the Brain's barrier during surgery may reveal hidden clues
NCT ID NCT07224451
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study explores whether temporarily opening the blood-brain barrier using a special electrical field during spine surgery can release brain-specific markers into the blood. Researchers will compare these blood markers to those found in spinal fluid from the same patient. If it works, it could pave the way for a simple blood test to diagnose brain and spinal cord diseases without a spinal tap.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Barrier disrupting fields (BDF) procedure
- What this could lead to
- If successful, this could lead to a less invasive way to detect brain and spinal cord conditions using a simple blood test instead of a spinal tap.
- What could go wrong
- This is a very early feasibility study with only 20 participants. The procedure is done under anesthesia during surgery, so results may not apply to awake patients or other settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sheba Medical Center
RECRUITINGRamat Gan, 52621, Israel
More trials for these conditions
Other studies related to the condition(s) this trial covers.