One shot gene therapy aims to halt vision loss in rare eye disorders

NCT ID NCT06460844

First seen Feb 26, 2026 · Last updated May 22, 2026 · Updated 12 times

Summary

This early-stage study tests a single injection of RTx-015 into the eye for people with retinitis pigmentosa or choroideremia, two inherited conditions that cause progressive vision loss. About 18 adults will receive one of four doses and be monitored for 5 years to check safety and any changes in eyesight. The goal is to see if the treatment is safe enough to move to larger trials.

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Contacts and locations

Locations

  • Retina Consultants of Texas Research Centers

    Bellaire, Texas, 77401, United States

  • Retina Vitreous Associates Medical Group

    Beverly Hills, California, 90211, United States

  • UCI Alpha Clinic

    Orange, California, 92868, United States

  • UPMC Vision Institute

    Pittsburgh, Pennsylvania, 15221, United States

Conditions

Explore the condition pages connected to this study.