Zap to see: electrical therapy for eye disease
NCT ID NCT02086890
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tests a treatment called transcorneal electrical stimulation to see if it can improve vision in people with retinitis pigmentosa, an eye disease that causes vision loss. Twenty-one adults with the condition received the therapy, and researchers measured changes in their visual field and sharpness over about 4-6 months. The goal is to find a way to ease symptoms and slow vision decline.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 21 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2014
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18+ * Diagnosis of retinitis pigmentosa (RP) * Best-corrected visual acuity better than 20/400 in at least one eye * More than 20% loss of Goldmann Visual Field area (III4e test target) in at least one eye * Able and willing to participate in all study visits for a \~4-6 month period * Provide informed consent Exclusion Criteria: * Very severe vision losses in both eyes (e.g., hand motions or light perception only) with difficulty performing the proposed vision tests * Vision loss due to ocular diseases other than RP, cystoid macular edema, or cataracts * Schedules do not permit participation in all study visits * Previous acupuncture or TES treatment for RP * Inability to understand study procedures or communicate responses to visual stimuli in a consistent manner (cognitive impairment) * Dementia; Long or short-term memory loss * Unable to read or speak English * Smoking, excessive alcohol, or illegal drug use * Receiving current psychiatric care (i.e. unstable emotional and mental health status) * History of excessive bleeding * Reduced general health and/or systemic medications that may diminish the potential response to the electroacupuncture treatments * Implanted cardiac pacemaker * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Nova Southeastern University; College of Optometry
Fort Lauderdale, Florida, 33328, United States
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Other studies related to the condition(s) this trial covers.
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