PROSTATE CANCER

This study aimed to find the lowest effective dose of the prostate cancer drug abiraterone. Researchers tested if taking a lower dose less frequently (like every other day or a few times a week) worked as well as the standard daily dose. The goal was to maintain cancer control wh…

This early-stage trial tested a new vaccine called VTP-850 for men whose prostate cancer has started to return after initial surgery or radiation. The goal was to see if the vaccine is safe and if it can train the body's immune system to fight the cancer, which would be shown by …

This early-stage study tested a new oral cancer drug called NUV-868, both alone and combined with existing medications (olaparib or enzalutamide), in adults with advanced solid tumors. The trial aimed to find safe doses and see if these treatments could help control cancers that …

This study tested a new approach to reduce side effects from radiation treatment for intermediate-risk prostate cancer. Researchers implanted a small, biodegradable balloon between the prostate and rectum to create space and protect healthy tissue. They measured if this allowed f…

This study tested whether a grape seed extract called OPC could reduce certain food-related substances (AGEs) in the blood of prostate cancer patients receiving hormone therapy. Researchers wanted to see if lowering AGE levels might help control cancer. The trial was terminated e…

This was a small, early-stage study to see if a new laser treatment system is safe and practical for treating prostate cancer. The system uses artificial intelligence (AI) software to map the cancer and guide a laser to precisely burn away the tumor while trying to avoid damaging…

This study tested an oral drug called pacritinib in men whose prostate cancer showed signs of returning after surgery or radiation. The main goal was to see if the drug could slow the rise of a blood marker called PSA. The trial was terminated early after enrolling only 6 partici…

This study tested whether using a new, advanced type of scan (PSMA-PET/MRI) could help doctors more accurately target radiation treatment for men with aggressive prostate cancer. The main goal was to see if this approach was safe and practical, and if it could help control the ca…

This study aimed to see if combining two drugs, cabozantinib and abiraterone, was safe and effective for men with advanced prostate cancer that had spread to their bones and was no longer responding to standard hormone therapy. Participants were assigned to receive different dose…

This study tested if combining two drugs, tivozanib and enzalutamide, could better control advanced prostate cancer that had stopped responding to standard hormone therapy. The goal was to see if the combination could delay cancer growth longer than using enzalutamide alone. The …

This was an early safety study for a new drug called acapatamab, designed to help the body's own immune cells attack advanced prostate cancer. It involved 212 men whose cancer had spread and was no longer responding to standard hormone and chemotherapy treatments. The main goal w…

This study tested a brief phone-based therapy to help patients and their partners cope with the emotional trauma of receiving news that their cancer is advanced and incurable. The therapy combined deep breathing exercises with a technique to help people structure their traumatic …

This study tested whether applying a special preserved placental tissue over nerves during prostate cancer surgery helps men regain erectile function and urinary control faster. Men with good pre-surgery sexual function were randomly assigned to receive the tissue or standard car…

This study aimed to see if an online video simulator helps surgeons learn a complex prostate cancer removal surgery. It compared surgeons trained with the simulator to those using standard training methods. The goal was to see if the simulator led to faster, safer surgeries with …

This study aimed to see if a special monitor could accurately tell doctors when a patient needs more fluids during robotic prostate cancer surgery. It tested 26 men having this specific operation. The goal was to gather knowledge to help guide fluid therapy more precisely in the …