Cure My Disease

Don't miss your cure!

 Log in / Sign up

New cancer drug trial halted early – what we know

NCT ID NCT05252390

Terminated Disease control Sponsor: Nuvation Bio Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested an experimental drug called NUV-868, alone or with other cancer drugs, in 82 adults with advanced solid tumors (including ovarian, pancreatic, prostate, and breast cancers). The goal was to find safe doses and check for early signs of effectiveness. However, the study was terminated early, so full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NUV-868 (an experimental oral drug)

What this could lead to

If successful, this could point toward a new treatment option for advanced solid tumors like ovarian, pancreatic, prostate, or breast cancer.

What could go wrong

This was a very early (Phase 1/2) trial that was terminated, so results are limited. The drug may not prove effective or safe in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PANCREATIC CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm castration-resistant prostate carcinoma exocrine pancreatic carcinoma fallopian tube cancer fallopian tube serous adenocarcinoma malignant pancreatic neoplasm metastatic prostate carcinoma neoplasm ovarian cancer ovarian serous adenocarcinoma pancreatic ductal adenocarcinoma pancreatic neoplasm primary peritoneal carcinoma prostate cancer prostate carcinoma prostate neoplasm Prostatic Neoplasms, Castration-Resistant triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED SOLID TUMOR BREAST CANCER BREAST CARCINOMA BREAST TUMOR CANCER OF BREAST CANCER OF OVARY CANCER OF PANCREAS CANCER OF PROSTATE CANCER OF THE BREAST CANCER OF THE OVARY CANCER OF THE PANCREAS CANCER OF THE PROSTATE CASTRATE RESISTANT PROSTATE CANCER CASTRATION RESISTANT PROSTATIC NEOPLASMS CASTRATION-RESISTANT PROSTATIC CANCER OVARIAN CANCER OVARY CANCER OVARY NEOPLASM PANCREAS CANCER PANCREAS NEOPLASM PANCREATIC CANCER PROSTATE CANCER PROSTATE NEOPLASM PROSTATIC CANCER TRIPLE NEGATIVE BREAST CANCER TRIPLE NEGATIVE BREAST NEOPLASMS

Contacts and locations

Locations

  • Cabrini Hospital Malvern

    Malvern, Victoria, 3144, Australia

  • Calvary Mater Hospital Newcastle

    Waratah, New South Wales, 2298, Australia

  • Carolina BioOncology Institute

    Huntersville, North Carolina, 28078, United States

  • Ellison Institute of Technology

    Los Angeles, California, 90064, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

  • H. Lee Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Laura & Isaac Perlmutter Cancer Center - NYU Langone Health

    New York, New York, 10016, United States

  • Linear Clinical Research

    Nedlands, Western Australia, 6009, Australia

  • Macquarie University Hospital

    North Ryde, New South Wales, 2109, Australia

  • Mary Crowley Cancer Research

    Dallas, Texas, 75230, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • NEXT Virginia

    Fairfax, Virginia, 22031, United States

  • Peter Maccallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Rocky Mountain Cancer Centers, LLP

    Aurora, Colorado, 80012, United States

  • Rocky Mountain Cancer Centers, LLP

    Lone Tree, Colorado, 80124, United States

  • Sarah Cannon Research Institute - Tennessee Oncology

    Nashville, Tennessee, 37203, United States

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    Baltimore, Maryland, 21231, United States

  • Texas Oncology - Fort Worth Cancer Center

    Fort Worth, Texas, 76104, United States

  • The University of Arizona Cancer Center

    Tucson, Arizona, 85724, United States

  • Virginia Oncology Associates

    Norfolk, Virginia, 23502, United States