Promising combo for prostate cancer falls short in early trial

NCT ID NCT01885949

First seen Mar 05, 2026 · Last updated May 11, 2026 · Updated 10 times

Summary

This study tested a combination of two drugs—enzalutamide (already approved for prostate cancer) and tivozanib (an experimental drug that cuts off a tumor's blood supply)—in men with advanced prostate cancer that had stopped responding to standard hormone therapy. The goal was to see if the combo could delay cancer growth longer than enzalutamide alone. Only 5 men enrolled before the study was ended early, so results are limited.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.