POSTOPERATIVE ANALGESIA

This study compares two types of ultrasound-guided nerve blocks to control pain after open colorectal surgery. About 50 adults aged 18 to 75 will be randomly assigned to receive one of the two blocks. The goal is to see which method provides better pain relief and reduces the nee…

This study compares three different nerve blocks (paravertebral, intertransverse, and erector spinae plane) to see which one best reduces pain and the need for strong painkillers after video-assisted lung surgery. About 96 adults having planned lung surgery will take part. The go…

This study tests if a nerve block (TAP block) is as good as or better than an epidural for pain after major abdominal cancer surgery. About 50 adults having surgeries like stomach, colon, or liver removal will be randomly assigned to one of the two methods. The goal is to see whi…

This study looks at whether a special ultrasound-guided nerve block (called Quadro-Iliac Plane Block) can help control pain after lumbar spine surgery. Researchers will follow 60 adults who are having elective back surgery and compare pain scores, opioid use, and side effects in …

This study compares two pain medicines, oliceridine and sufentanil, given through a patient-controlled pump after brain surgery. The goal is to see if oliceridine causes less nausea, a common side effect of painkillers. About 174 adults having surgery in the back of the skull wil…

This study looks at whether combining two types of nerve blocks can lower the amount of strong painkillers (opioids) needed after heart surgery and improve recovery. Researchers will enroll 90 adults having planned heart surgery. The goal is to find a safer way to manage pain and…

This study tests a new medicine called HRS-2129 to see if it can safely reduce pain after abdominal surgery. About 360 adults having belly surgery will receive either the new drug or a comparator. The main goal is to measure pain relief over the first 48 hours after treatment.

This study compares two types of nerve blocks (PENG block and L-ESP block) to see which one provides better pain relief after total hip replacement surgery. About 52 adults having hip replacement will receive one of the blocks, and researchers will measure their pain scores, opio…

This study compares two ways to dilute a numbing medicine (bupivacaine) for arm blocks before surgery. One uses sugar water (D5W), the other uses salt water (normal saline). Researchers want to see which helps the block work faster and last longer. About 90 adults having arm surg…

This study looks at two different methods to control pain after laparoscopic hernia repair. Sixty adults having this surgery will be randomly assigned to receive either a numbing injection into the belly wall or a targeted nerve block guided by ultrasound. The goal is to find whi…

This study compares two types of ultrasound-guided pain blocks for children aged 6 months to 16 years having laparoscopic (keyhole) belly surgery. One block numbs nerves between the belly muscles, and the other targets deeper nerves. Researchers will measure pain scores, how long…

This study tests two different doses of a pain medicine called ketorolac given through a vein after a planned C-section. The goal is to see which dose provides better pain relief. About 126 women having a planned C-section will take part and rate their pain on a 0-10 scale.

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during weight-loss surgery can lower pain, inflammation, and cell stress afterward. About 104 adults having laparoscopic bariatric surgery will be randomly assigned to receive the combo, on…

This study compares two types of nerve blocks (PENG block and Deep Iliacus Plane Block) to see which provides better pain relief for people with hip fractures. The blocks are tested during positioning for spinal anesthesia and after surgery. The goal is to find which method reduc…

This study tests whether a specific nerve block (erector spinae plane block) can reduce pain after laparoscopic abdominal surgery. 50 adults undergoing these surgeries will receive the block or standard care. The main goal is to see how long it takes before they need extra pain m…

This study tests if a special nerve block, called SPSIPB, can improve recovery and reduce pain after minimally invasive heart bypass surgery. Sixty adults will be randomly assigned to receive either the nerve block plus standard care, or standard care alone. The goal is to see if…

This study tests whether a long-acting numbing medicine (bupivacaine liposome) can provide better pain relief after lung surgery compared to standard numbing medicine. About 496 adults having a lung lobe removed will receive a nerve block before surgery. The goal is to reduce pai…

This study compares two types of nerve blocks (ESP block and TAP block) to see which one better controls pain after open appendix removal. About 68 adults having open appendectomy will receive one of the two blocks before surgery. The main goal is to measure how much morphine the…

This study compares two types of nerve blocks (RIPB and EOIPB) to see which one provides better pain relief after gallbladder removal surgery. About 60 adults having laparoscopic cholecystectomy will receive one of the two blocks. The main goal is to measure how much pain medicat…

This study is observing 90 adults who are having open heart surgery to compare three standard pain relief methods: IV pain medicine, an epidural, or a nerve block. The main goal is to see which method is best at preventing chronic pain that lasts 3 months after surgery. Researche…