POLYCYSTIC OVARY SYNDROME

This study looked at whether inositol, a natural supplement, can improve ovulation in women with polycystic ovary syndrome (PCOS) who did not respond to the fertility drug letrozole. 36 women aged 18-35 took part. The researchers compared inositol to metformin, another common tre…

This study tested two approaches to help women with PCOS who did not ovulate after standard letrozole treatment. One group took letrozole for 7 days instead of 5, and the other took letrozole plus inositol. The goal was to see which method led to more ovulations and pregnancies. …

This study tested whether adding dapagliflozin (a diabetes drug) or metformin to the standard fertility drug letrozole helps women with polycystic ovary syndrome (PCOS) ovulate and become pregnant. 200 women participated. The goal was to see if these combinations improve ovulatio…

This study looked at whether a traditional Chinese herbal mixture (Zishen Qingre Lishi Huayu) can help women with polycystic ovary syndrome (PCOS) ovulate more regularly. The trial involved 126 women aged 20 to 40 and used a double-blind, placebo-controlled design to measure ovul…

This pilot study tested whether adding krill oil to standard metformin therapy improves metabolic health in women with PCOS and obesity. Fifty-four women were split into three groups: metformin alone, krill oil alone, or both together for 8 weeks. Researchers measured changes in …

This study compared two lifestyle approaches—intermittent fasting (eating only during an 8-hour window) and resistive exercise (like weight training)—for improving insulin resistance in 72 obese women with polycystic ovary syndrome (PCOS). The goal was to see which method is more…

This study looked at whether acupuncture (personalized or fixed) or the drug letrozole could help women with polycystic ovary syndrome (PCOS) have a baby. Over 1,100 women took part, receiving treatment for 16 weeks. The main goal was to see which approach led to more live births…

This study looked at whether a type of diabetes drug called SGLT2 inhibitors can help women with Polycystic Ovary Syndrome (PCOS) better than the standard drug metformin. The researchers believe these drugs may work by reducing inflammation in the body. The study involved 82 wome…

This study tested whether umbilical cord stem cells and their secretions (secretomes) can help women with polycystic ovary syndrome (PCOS) who also have insulin resistance. 44 women received either stem cells, secretomes, both, or a control treatment. The goal was to see if these…

This study looked at 192 women with PCOS to see which treatment works best for improving insulin resistance and other symptoms. Participants were randomly assigned to take metformin, inositol, follow a calorie-restricted diet, or combine all three for 12 weeks. The goal was to fi…

This study tested whether inositol, a natural dietary supplement, can lower high testosterone levels in women with polycystic ovary syndrome (PCOS). 154 women took either a placebo or one of three doses of inositol powder for a set period. Researchers measured changes in testoste…

This study looked at whether using a contraceptive vaginal ring (NuvaRing) for 16 weeks affects the risk of metabolic syndrome in overweight or obese women with polycystic ovary syndrome (PCOS). Researchers enrolled 22 participants and measured changes in blood pressure, waist si…

This study looked at whether a supplement called NMN can help women with polycystic ovary syndrome (PCOS). The researchers measured changes in hormone levels, ovarian health, and menstrual cycles. 88 women aged 20-40 with a BMI under 25 took part. The goal was to see if NMN could…

This study looked at whether taking birth control pills every day for 6 months (continuous) works better than the usual 3-weeks-on, 1-week-off schedule for women with Polycystic Ovary Syndrome (PCOS). The goal was to see which approach lowers testosterone levels and improves symp…

This study tested whether the drug metformin can improve fertility-related hormones and reduce inflammation in women with polycystic ovary syndrome (PCOS). 110 women with PCOS took metformin for 8 weeks and provided blood samples and symptom reports. The goal was to see if metfor…

This study looked at whether a diet-only or a diet-plus-exercise program works better for obese women with polycystic ovary syndrome (PCOS). Twenty-seven women were split into two groups: one received dietary advice, the other got both diet and personalized exercise recommendatio…

This study looked at whether time-restricted eating (eating only during certain hours) combined with a Mediterranean diet could help women with polycystic ovary syndrome (PCOS). Fifty-five women with PCOS and a BMI between 25-35 took part. The goal was to see if these diet change…

This study tested whether a special supplement containing antioxidants and probiotics could improve egg quality in women with polycystic ovary syndrome (PCOS) undergoing IVF. Twenty women took either the supplement or a placebo (just folic acid) during their IVF cycle. Researcher…

This study tested whether daily text messages and small financial rewards could motivate overweight teens and young adults with prediabetes or type 2 diabetes to be more physically active. 75 participants wore a Fitbit and received different combinations of texts and incentives o…

This study looked at 100 women with Polycystic Ovary Syndrome (PCOS) to understand how the condition impacts their quality of life and mental health. Researchers examined factors like age, weight, how long it took to get a diagnosis, and history of anxiety or depression. Particip…

This completed study used 2D and 3D ultrasound to measure uterine and endometrium volume in 648 women with PCOS or HPOD, two conditions that cause irregular periods. The goal was to see if these measurements could help tell the two disorders apart. The study did not test any trea…

This completed study looked at how ovulation disorders affect quality of life in nearly 1,000 women aged 18-45 with irregular periods. Participants filled out a 36-question survey covering physical, emotional, and social well-being. The goal was to compare two groups: those with …

This study looked at 300 women with different types of PCOS and healthy women to see if kidney function and urine protein levels differ. Researchers measured urine albumin-to-creatinine ratio and estimated glomerular filtration rate. The goal was to understand if certain PCOS typ…

This study created and tested a new questionnaire to measure both the severity of Polycystic Ovary Syndrome (PCOS) symptoms and the distress they cause. Researchers enrolled 227 women diagnosed with PCOS in Turkey. Participants completed online surveys, including the new inventor…

This study looked at 58 pregnant women with and without PCOS to understand how hormones like AMH and leptin might be passed to their babies. Researchers measured these hormones in the mother's blood during each trimester and in the placenta after birth. The goal was to see if hig…

This study used advanced MRI scans to look at the hypothalamus, a brain region that controls hormones, in women with PCOS. Researchers compared 52 women with and without PCOS to see if there were differences in brain structure and chemistry. The goal was to better understand how …

This early study tested whether giving a continuous infusion of kisspeptin, a natural hormone, could dampen the overactive reproductive signals seen in polycystic ovary syndrome (PCOS). Eight women with PCOS received the hormone for 24 hours, and researchers measured changes in t…

This completed study looked at 70 adolescent girls with PCOS and 40 healthy teens to see if vitamin D levels are linked to metabolic problems like insulin resistance. Researchers measured vitamin D, blood sugar, cholesterol, and belly fat thickness using ultrasound. The goal was …