OBSESSIVE - COMPULSIVE DISORDER

This study is testing an experimental brain implant that stimulates two connected brain areas to treat severe obsessive-compulsive disorder (OCD) that hasn't improved with standard therapies. Only 2 participants with extremely severe, long-lasting OCD symptoms will receive the im…

This study aimed to improve deep brain stimulation (DBS) treatment for severe obsessive-compulsive disorder (OCD). Researchers wanted to use advanced brain imaging to help surgeons place the stimulation device more precisely in each patient's unique brain anatomy. The goal was to…

This study is testing how well a combination of medication and a specific type of talk therapy (cognitive behavioral therapy) helps people with various mental health conditions. It involves 107 adults with diagnoses like anxiety, depression, PTSD, bipolar disorder, or schizophren…

This study aims to see which of two common talk therapies—Cognitive Behavioral Therapy (CBT) or Brief Strategic Therapy (BST)—is more effective for teenagers with anxiety, depression, or obsessive-compulsive disorder. Researchers will observe 192 teens aged 12-20 who are already …

This study is testing whether a medication called tolcapone can help reduce symptoms of obsessive-compulsive disorder (OCD). Researchers are comparing tolcapone against a placebo in 49 adults with moderate to severe OCD over 8 weeks. The study also examines how the medication aff…

This pilot study aims to see if it's practical to run a larger trial comparing two types of cognitive-behavioral therapy (CBT) for anxiety. It tests a single, unified therapy approach against several specific therapies tailored to different anxiety disorders. The study enrolled 7…

This study is testing whether a mindfulness-based therapy program can effectively reduce symptoms of Obsessive-Compulsive Disorder (OCD). It involves 420 participants across two Canadian clinics, comparing the mindfulness program to standard cognitive-behavioral therapy and a wai…

This study is testing whether taking two doses of psilocybin, the active compound in 'magic mushrooms,' can reduce symptoms of obsessive-compulsive disorder (OCD). It involves 30 adults with moderate-to-severe OCD who haven't gotten better with standard medications or therapy. Pa…

This study aims to see if brain inflammation levels can predict how well people with OCD respond to an anti-inflammatory medication. Researchers will use brain scans and blood tests to measure inflammation in 21 adults with OCD who are still experiencing symptoms despite current …

This study is testing whether a gentle, non-invasive brain stimulation technique can help people with severe obsessive-compulsive disorder (OCD) who haven't gotten better with standard therapies like medication and therapy. Researchers are using a device that sends a very low ele…

This study is testing whether cognitive behavioral therapy (CBT), a common talk therapy, is effective when provided by supervised but unlicensed trainees. It aims to see if this approach can help more people get access to proven mental health treatments for conditions like anxiet…

This study aims to understand why some people with obsessive-compulsive disorder (OCD) respond to medications or brain stimulation treatments while others don't. Researchers will study 60 adults with OCD, grouping them by how well they respond to standard medications or two types…

This Stanford University study aims to use MRI brain scans to predict which type of brain stimulation treatment will work best for people with obsessive-compulsive disorder (OCD). Researchers are studying 212 adults with moderate to severe OCD who haven't improved with standard t…