OBSESSIVE-COMPULSIVE DISORDER

This study looks at whether combining medication with one-on-one cognitive behavioral therapy helps people with mental health disorders like anxiety, depression, bipolar disorder, and schizophrenia. 107 adults aged 18-65 with an IQ of 80 or higher took part. The goal is to see if…

This study tests a brain implant (deep brain stimulation) in 2 people with severe obsessive-compulsive disorder (OCD) that hasn't improved with standard treatments. The device sends electrical pulses to specific brain areas to help control symptoms. The goal is to reduce OCD seve…

This early-phase study tests whether psilocybin, the active ingredient in magic mushrooms, can safely help reduce symptoms of obsessive-compulsive disorder (OCD). Thirty-five adults with OCD who have not responded well to standard treatments will receive psilocybin in a controlle…

This study tests whether tolcapone, a drug currently used for Parkinson's disease, can safely reduce symptoms in adults with moderate to severe obsessive-compulsive disorder (OCD). About 49 participants will receive either tolcapone or a placebo to see if it improves OCD severity…

This study tests a non-invasive brain stimulation method called tDCS for people with obsessive-compulsive disorder (OCD) who haven't gotten better with standard treatments like therapy or antidepressants. About 43 participants will receive low-level electrical current through ele…

This study looks at whether unlicensed professionals can provide cognitive behavioral therapy (CBT) to people with conditions like anxiety, depression, OCD, and PTSD. About 250 participants will receive therapy at Massachusetts General Hospital. The goal is to see if their mental…

This study looks at whether measuring inflammation in the brain and blood can predict how much people with obsessive-compulsive disorder (OCD) will benefit from adding the anti-inflammatory drug celecoxib to their current medication. The goal is to see if a personalized approach …

This study tests if a non-invasive brain stimulation technique called TMS can make exposure therapy work better for young people with OCD. Fifty participants aged 12 to 21 will receive daily TMS followed by therapy for two weeks. Researchers will compare real TMS to a fake versio…

This study is testing whether repeated doses of psilocybin, the active ingredient in magic mushrooms, can reduce symptoms of obsessive-compulsive disorder (OCD). It involves 30 adults with severe OCD who have not improved with standard treatments. Participants receive psilocybin …

This study tests whether a short mindfulness program can reduce the distress of obsessive-compulsive disorder (OCD). About 420 adults with OCD will receive either mindfulness training or standard therapy. Researchers will measure changes in OCD symptoms and explore how mindfulnes…

This study explores whether a new type of group therapy, called natural psychotherapy, can help people with anxiety disorders. Sixty adults aged 15 to 55 with obsessive-compulsive disorder will take part. The therapy is based on Eastern cultural ideas and focuses on reducing anxi…

This study looks at whether it's possible to compare a general therapy approach (transdiagnostic) with a specific one (diagnosis-specific) for people with anxiety disorders like panic disorder or social anxiety. Researchers want to see if they can recruit enough participants, kee…

This study looks at 60 people with obsessive-compulsive disorder (OCD) who either respond well to medication or brain stimulation, or don't respond at all. Researchers will take blood samples and turn them into nerve cells in the lab to study how these cells react to different tr…

This study is for people with severe, hard-to-treat OCD. Researchers are testing an advanced brain stimulation system that can adapt to brain signals. The goal is to find reliable brain markers of OCD distress, which could lead to better treatments in the future. Only 2 participa…

This study was designed to find better ways to target deep brain stimulation (DBS) for people with severe obsessive-compulsive disorder (OCD). Researchers planned to use brain scans to personalize the placement of electrodes. However, the study was withdrawn before enrolling any …

This study will follow 192 teenagers aged 12 to 20 who are already receiving either Cognitive Behavioral Therapy (CBT) or Brief Strategic Therapy (BST) for conditions like anxiety, depression, or OCD. Researchers will track their progress using questionnaires and interviews over …

This study from Stanford University is looking at whether brain scans can help predict which people with Obsessive-Compulsive Disorder (OCD) will respond to a non-invasive brain stimulation treatment called rTMS. Researchers will scan the brains of 212 adults with OCD and then gi…

This early-phase study is testing a new type of deep brain stimulation (DBS) that automatically adjusts based on brain signals in people with severe, treatment-resistant OCD. Only 2 participants are enrolled to help researchers identify brain activity patterns linked to OCD distr…