Brain implant learns to read OCD signals in real time

NCT ID NCT04281134

Ongoing Knowledge-focused Sponsor: Baylor College of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an adaptive deep brain stimulation (aDBS) system in just 3 people with severe, treatment-resistant OCD. The device is implanted in the brain and chest, and it aims to detect brain signals linked to OCD distress and adjust stimulation automatically. The main goal is to see if the system can reliably identify those signals, not yet to prove it improves symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Deep brain stimulation (DBS) device
What this could lead to: If it works, this could point toward a smarter, more personalized DBS system that adjusts stimulation in real time to better control severe OCD symptoms.
What could go wrong: This is a very early, tiny study (only 3 participants) focused on finding brain signals, not on proving the treatment works. The approach may not lead to a reliable therapy, and DBS surgery carries risks like infection or brain injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBSESSIVE-COMPULSIVE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

obsessive-compulsive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBSESSIVE-COMPULSIVE DISORDER

Contacts and locations

Locations

Baylor College of Medicine

Houston, Texas, 77030, United States
Brown University

Providence, Rhode Island, 02912, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15260, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.