OBSESSIVE COMPULSIVE DISORDER
Clinical trials for OBSESSIVE COMPULSIVE DISORDER explained in plain language.
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Brain implant trial offers hope for most severe OCD cases
Disease control Not yet recruitingThis study is testing whether a surgically implanted brain stimulation device can help people with severe obsessive-compulsive disorder (OCD) that hasn't responded to other treatments. Ten participants will have a device implanted that can both stimulate the brain and record its …
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Phase: NA • Sponsor: Nader Pouratian • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Zapping the brain to quiet OCD's inner alarm
Disease control Not yet recruitingThis study aims to understand and potentially treat the unusual sensory feelings that often drive compulsive behaviors in people with Obsessive-Compulsive Disorder (OCD). Researchers will use brain scans and a non-invasive magnetic stimulation technique (rTMS) on a specific brain…
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Phase: NA • Sponsor: Shanghai Mental Health Center • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Brain zap breakthrough: triggering symptoms before treatment could help severe OCD
Disease control Not yet recruitingThis study tests whether briefly triggering obsessive-compulsive symptoms right before brain stimulation makes the treatment more effective for people with severe OCD who haven't responded to standard treatments. Researchers will compare two groups: one receiving only brain stimu…
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Phase: NA • Sponsor: Centre Hospitalier Henri Laborit • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Sound waves target brain to treat untreatable OCD
Disease control Not yet recruitingThis study is testing whether focused ultrasound can safely reduce symptoms of obsessive-compulsive disorder (OCD) in people who haven't improved with standard treatments like therapy and medications. Researchers will use MRI-guided sound waves to target a specific brain area wit…
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Phase: PHASE1, PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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Brain pacemaker tested for most severe OCD cases
Disease control Not yet recruitingThis is a small, early-stage study to see if deep brain stimulation (DBS) can help people with severe obsessive-compulsive disorder (OCD) that hasn't improved with other treatments. Four participants will have a device implanted to deliver mild electrical pulses to two different …
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Phase: NA • Sponsor: Rhode Island Hospital • Aim: Disease control
Last updated Mar 18, 2026 14:41 UTC
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Magic mushroom compound tested as new hope for Tough-to-Treat OCD
Disease control Not yet recruitingThis study is testing whether psilocybin, the active compound in 'magic mushrooms,' can help people with OCD when standard treatments haven't worked well enough. Twenty adults with moderate to severe OCD will be randomly assigned to receive either a low or high dose of psilocybin…
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Phase: PHASE1, PHASE2 • Sponsor: Francisco A Moreno • Aim: Disease control
Last updated Mar 09, 2026 14:22 UTC
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Self-Help booklet trial offers hope for OCD sufferers in pakistan
Symptom relief Not yet recruitingThis study aims to test a culturally adapted self-help workbook for obsessive-compulsive disorder (OCD) in Pakistan, where access to trained therapists is limited. The workbook is based on cognitive behavioral therapy (CBT) principles and includes guidance from a therapist. Resea…
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Phase: NA • Sponsor: Pakistan Association of Cognitive Therapists • Aim: Symptom relief
Last updated Apr 01, 2026 14:40 UTC
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One-Hour online session aims to ease burden for OCD caregivers
Symptom relief Not yet recruitingThis study is testing a free, one-time online program designed to help caregivers of children with Obsessive-Compulsive Disorder (OCD). The program teaches caregivers how to reduce stress and change certain caregiving behaviors that might accidentally make a child's OCD symptoms …
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Phase: PHASE1 • Sponsor: Boston University Charles River Campus • Aim: Symptom relief
Last updated Mar 30, 2026 14:35 UTC
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New hope for OCD? brain drug trial seeks to ease unwanted thoughts
Symptom relief Not yet recruitingThis study is testing whether a medication called valbenazine can safely reduce the severity of obsessive-compulsive disorder (OCD) symptoms. It will involve 30 adults with moderate-to-severe OCD. Each participant will try both the study drug and a placebo for 6 weeks each to see…
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Mar 23, 2026 15:19 UTC
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Researchers investigate hidden link between addiction and obsessive thoughts
Knowledge-focused Not yet recruitingThis study aims to understand how common obsessive-compulsive symptoms are in people recovering from substance use disorders. Researchers will compare 51 adults with substance use disorders to 51 healthy adults, using questionnaires and interviews to measure symptoms and quality …
Matched conditions: OBSESSIVE COMPULSIVE DISORDER
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC