Brain scans and Decision-Making tasks aim to uncover OCD's hidden markers
NCT ID NCT03313622
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study looks for brain-based markers (biomarkers) of obsessive-compulsive disorder (OCD) in people with severe, hard-to-treat symptoms. Participants complete decision-making tasks and are exposed to personal OCD triggers while their brain activity is recorded with EEG and their facial reactions are filmed. The goal is to better understand the brain circuits involved in OCD, which could eventually lead to more personalized treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could identify measurable brain signals linked to OCD symptoms, paving the way for more targeted treatments.
- What could go wrong
- This is a small, early-stage observational study focused on discovery, not treatment. It may not yield clear or generalizable biomarkers.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Brown University
Providence, Rhode Island, 02912, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15260, United States
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