Can mindfulness beat OCD? large trial aims to find out
NCT ID NCT04914923
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tests whether mindfulness-based therapy can help people with obsessive-compulsive disorder (OCD). Researchers will compare mindfulness to standard cognitive behavioural therapy (CBT) in 420 adults with OCD. The goal is to see if mindfulness reduces OCD symptoms and to understand how it works.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Mindfulness-Based Cognitive Therapy (MBCT) and Cognitive Behaviour Therapy (CBT)
- What this could lead to
- If it works, this could offer a new, non-drug treatment option for OCD that helps reduce symptoms and improve quality of life.
- What could go wrong
- This is a mid-stage study, and previous small studies have shown mixed results. It may not prove more effective than existing therapies, and benefits may vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
St. Joseph's Healthcare Hamilton
Hamilton, Ontario, L8N 4A6, Canada
-
Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can improv comedy help tame OCD?
- A Two-Year watch: can brain scans and surveys predict depression and anxiety in teens?
- Therapy may let kids with OCD ditch meds for good
- Could gut bacteria hold the key to childhood OCD?
- Can brain recordings unlock better OCD treatment?