NICOTINE DEPENDENCE
Clinical trials for NICOTINE DEPENDENCE explained in plain language.
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New therapy tackles smoking and mental health together for people with HIV
Disease control CompletedThis study tested a special therapy program designed to help people living with HIV quit smoking. The program focused on reducing anxiety and depression, which are common challenges that make quitting harder. Researchers compared this 9-session therapy to standard quit-smoking ad…
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Can free E-Cigs help heavy smokers smoke less?
Disease control CompletedThis small pilot study tested whether providing free e-cigarettes for 4 weeks could help heavy smokers who don't plan to quit reduce their cigarette smoking. Researchers enrolled 15 people who had previously tried to quit and gave them e-cigarettes to use instead of regular cigar…
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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One pill, two addictions? study tests drug for drinking and smoking
Disease control CompletedThis study tested whether a medication called topiramate could help people who struggle with both alcohol dependence and smoking. Over 200 participants received either the medication or a placebo, along with counseling, and were followed to see if they could reduce heavy drinking…
Matched conditions: NICOTINE DEPENDENCE
Phase: PHASE2, PHASE3 • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Can a whiff of lemongrass help you quit smoking?
Disease control CompletedThis study tested whether using lemongrass in an inhaler or as a scented vapor could help adult smokers feel less dependent on nicotine. Researchers compared 200 young adult smokers who used lemongrass products to a group that did not. They checked if it changed cravings, stress …
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: Titin Andri Wihastuti • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Magnetic pulses to the brain aim to curb smoking cravings
Symptom relief CompletedThis study tested whether two types of non-invasive magnetic brain stimulation could reduce nicotine craving. It compared the effects in 90 participants: people with schizophrenia who smoke and people without psychosis who smoke. The main goal was to see if stimulating specific b…
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Mar 19, 2026 14:56 UTC
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Scientists scan brains to crack Addiction's code
Knowledge-focused CompletedThis study aimed to create and test new computer tasks to use during brain scans, helping researchers understand how drug use affects thinking and decision-making. Researchers worked with 525 volunteers, including both people who use drugs and those who don't, to develop these ta…
Matched conditions: NICOTINE DEPENDENCE
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Scientists scan brains to crack the code of smoking addiction
Knowledge-focused CompletedThis study aimed to understand why some people find it harder to quit smoking than others. Researchers used brain scans (MRIs) and genetic tests on 159 smokers, former smokers, and non-smokers to look for patterns linked to addiction. The goal was to gather information that could…
Matched conditions: NICOTINE DEPENDENCE
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Scientists test how nicotine 'Salts' in vapes hit your bloodstream
Knowledge-focused CompletedThis study aimed to understand how nicotine from two different types of vaping liquid—'salt-based' and 'free-base'—gets into the bloodstream and affects users. Researchers had 15 daily vapers try four different e-liquids to measure nicotine levels in their blood and ask about the…
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: Roswell Park Cancer Institute • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:07 UTC