Can a seizure drug curb both drinking and smoking?

NCT ID NCT01182766

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 34 times

Summary

This study tested whether topiramate, a seizure medication, helps people who are dependent on both alcohol and nicotine. 236 adults took either a high or low dose of topiramate or a placebo for 18 weeks. The main goals were to see if the drug helped them stop smoking and reduce heavy drinking days.

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Contacts and locations

Locations

  • University of California, San Diego

    La Jolla, California, 92093, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of Virginia Center for Addiction Research & Education

    Charlottesville, Virginia, 22911, United States

  • University of Virginia Center for Addiction Research & Education

    Richmond, Virginia, 23294, United States

Conditions

Explore the condition pages connected to this study.