NICOTINE DEPENDENCE
Clinical trials for NICOTINE DEPENDENCE explained in plain language.
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Nudge study aims to help HIV smokers quit
Disease control ENROLLING_BY_INVITATIONThis study looks at whether sending reminders (nudges) to doctors, patients, or both can increase the number of people with HIV who smoke getting help to quit. About 500 patients and their doctors are involved. The goal is to see if these nudges lead to more referrals and partici…
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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E-Cigarettes may dull the Brain's response to smoking triggers
Disease control OngoingThis study investigates whether using an electronic cigarette, along with a nicotine patch, can lessen smokers' automatic reactions to smoking-related cues like seeing someone smoke or smelling cigarette smoke. The researchers will measure these reactions through questionnaires, …
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: Mclean Hospital • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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New hope for depressed smokers: therapy plus quit support shows promise
Disease control OngoingThis study tested whether adding a special type of talk therapy (CBASP) to standard smoking cessation treatment helps depressed smokers quit and feel better. About 91 adults with depression who smoked at least 5 cigarettes a day took part. The goal was to see if the combined appr…
Matched conditions: NICOTINE DEPENDENCE
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New study aims to help smokers with HIV kick the habit for good
Disease control OngoingThis study tests whether a smoking cessation medication (varenicline) combined with tools to help people stick with treatment can improve quit rates for smokers living with HIV. About 340 participants will be followed for 6 months to see if they stop smoking, confirmed by breath …
Matched conditions: NICOTINE DEPENDENCE
Phase: PHASE3 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Can jobs and friendships beat addiction? new study tests community approach
Disease control ENROLLING_BY_INVITATIONThis study tests a program called the Bridge Model that provides social support, volunteering, and job opportunities to help people with nicotine or substance use disorders who are homeless or low-income. Researchers want to see if this approach improves quality of life and helps…
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: Ottawa Hospital Research Institute • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Could a sleep medication curb nicotine cravings?
Symptom relief OngoingThis study tests whether suvorexant, a drug used for insomnia, can reduce nicotine cravings and withdrawal symptoms in daily smokers. Participants, who smoke at least 5 cigarettes a day and are nicotine-dependent, will receive either a low or high dose of suvorexant or a placebo.…
Matched conditions: NICOTINE DEPENDENCE
Phase: PHASE1 • Sponsor: Mclean Hospital • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Pain relief study for smokers after lung surgery pulled before it started
Symptom relief TerminatedThis study aimed to see if adding dexmedetomidine to a standard painkiller could improve pain control and comfort after lung surgery in smokers. It planned to enroll 102 men with high nicotine dependence. However, the study was withdrawn before any participants were enrolled, so …
Matched conditions: NICOTINE DEPENDENCE
Phase: PHASE4 • Sponsor: Shenyang Sixth People's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Relighting your cigarette? study says it may boost toxins
Knowledge-focused OngoingThis study aims to understand if relighting a cigarette (smoking it in parts) produces more harmful chemicals than smoking it all at once. Researchers will observe 30 smokers who already relight their cigarettes, measuring their smoking habits and collecting cigarette butts. No t…
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Study on mail ads and smoking pulled before it started
Knowledge-focused TerminatedThis study was designed to understand how cigarette direct mail marketing influences smoking beliefs and behavior in young adults ages 18 to 29. Researchers planned to compare responses between smokers from higher and lower income backgrounds. However, the study was withdrawn bef…
Matched conditions: NICOTINE DEPENDENCE
Phase: NA • Sponsor: National Institute on Minority Health and Health Disparities (NIMHD) • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Can radiation help kick the habit? new study explores smoking cessation in cancer patients
Knowledge-focused OngoingThis study follows 100 head and neck or lung cancer patients who are current or former smokers and receive radiation therapy. Researchers track who stays smoke-free at 1, 6, and 12 months after treatment ends, and what factors help or hinder abstinence. The goal is to learn how t…
Matched conditions: NICOTINE DEPENDENCE
Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC