LUNG NON-SMALL CELL CARCINOMA

This study is testing a more precise way to deliver radiation therapy to people whose lung cancer, melanoma, or kidney cancer has spread to a few new spots. It uses PET scans to guide the radiation beams to the most active parts of the tumors. The goal is to see if this targeted …

This study is testing whether a structured home exercise program can improve how well immunotherapy works for people with non-small cell lung cancer. Researchers want to see if regular aerobic exercise on a stationary bike can boost the body's immune activity, helping the treatme…

This study is testing a minimally invasive procedure called TACE for patients with advanced lung cancer or cancer that has spread to the lungs. TACE works by injecting chemotherapy directly into the artery feeding the tumor and then blocking that artery to cut off the tumor's blo…

This early study is testing if adding a low-dose immune stimulant (IL-2) to a standard immunotherapy drug (pembrolizumab) can better fight advanced non-small cell lung cancer. The main goal is to see how this combination changes the patient's immune cells. Researchers will also c…

This study is for people with early-stage non-small cell lung cancer who have had surgery and whose initial treatment completely removed the cancer. It compares two approaches: one group receives a year of immunotherapy (durvalumab) to try to prevent the cancer from returning, wh…

This study tests whether combining a specialized radiation technique called grid therapy with standard immunotherapy can help control advanced lung cancer that has worsened despite current treatments. Grid therapy delivers high radiation doses to small tumor areas, potentially ki…

This study is testing whether giving two immunotherapy drugs before surgery can help the body's immune system attack and shrink early-stage non-small cell lung cancer. The goal is to kill more cancer cells before the tumor is removed, potentially leading to better long-term resul…

This large, late-stage trial is testing if adding an immunotherapy drug (pembrolizumab) to standard chemotherapy helps patients live longer without their cancer returning. It is for people with stage II or III non-small cell lung cancer who have already had their tumor surgically…

This study is testing a new, injectable drug called amivantamab for people with advanced non-small cell lung cancer that has a specific genetic feature called MET amplification. The drug is designed to target and reduce the extra copies of the MET gene in the tumor, which may hel…

This study is testing whether artificial intelligence (AI) software can help doctors determine the best radiation dose for each patient's lung tumor. It aims to see if this personalized approach can better control the cancer and reduce side effects compared to standard dosing. Ab…

This early-stage study is testing a drug called gilteritinib in patients with advanced, ALK-positive non-small cell lung cancer that has stopped responding to other targeted treatments. The main goals are to find the safest dose and understand the side effects. Researchers are st…

This study is testing whether giving a cancer immunotherapy treatment called nivolumab as an injection at home is a safe and practical alternative to receiving it at a clinic. It aims to see if home treatment reduces the burden of travel and improves quality of life for patients …

This study is testing whether psilocybin, the active compound in 'magic mushrooms,' combined with therapy, is safe and helpful for treating depression in people with non-small cell lung cancer. It involves 10 participants who will take a single dose of psilocybin during a guided …

This study is testing whether a yoga program for patients and their caregivers can improve physical function and quality of life during radiation treatment for lung or esophageal cancer. It will compare yoga sessions to educational sessions to see which helps patients walk farthe…

This study aims to understand if using cannabis or related products helps people manage symptoms like pain and nausea during cancer treatment. It will follow 2,000 adults newly diagnosed with certain cancers who are starting chemotherapy or immunotherapy. Researchers will track p…

This study aims to identify early warning signs of lung inflammation (pneumonitis) in patients with non-small cell lung cancer who receive combined chemotherapy, radiation, and immunotherapy. Researchers will collect blood, saliva, and stool samples from 150 participants and moni…

This study is testing whether a special communication tool helps doctors and patients with non-small cell lung cancer make treatment decisions together more effectively. The tool guides conversations about treatment options, benefits, and risks while considering each patient's pe…

This study aims to see if providing patients with quality-of-life information helps them make better decisions about their early-stage lung cancer treatment. It compares two groups: one receives a fact sheet about life after surgery or radiation, and the other receives standard c…

This study aims to understand if the order a surgeon cuts the blood vessels during lung cancer surgery affects how much cancer DNA is left in the bloodstream afterward. Researchers will compare two standard techniques—cutting the vein first versus cutting the artery first—in 100 …

This study is a survey asking lung cancer patients about their experiences with immunotherapy treatments. Researchers want to understand if patients find their current treatments safe and convenient, and whether they would prefer receiving future treatments as an injection at hom…

This study is collecting tissue and blood samples from cancer patients over time to create a research resource called a biobank. Researchers will analyze these samples to understand how cancer changes during treatment and why some treatments stop working. The goal is to help scie…

This study aims to understand the real-life challenges and supports for people getting diagnosed and treated for non-small cell lung cancer, specifically if they have a history of alcohol or substance use. Researchers will interview 45 patients who have been through treatment to …

This study aims to understand why some cancer patients develop severe diarrhea and colon inflammation (colitis) while taking powerful immunotherapy drugs called immune checkpoint inhibitors. Researchers will collect stool, blood, and tissue samples from 800 patients with melanoma…