Magic mushroom compound tested for depression in lung cancer patients
NCT ID NCT07216404
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether psilocybin (the active ingredient in magic mushrooms) combined with therapy is safe and helpful for people with non-small cell lung cancer who also have major depression. Ten participants will receive psilocybin in a controlled setting along with counseling sessions. The goal is to see if this approach can reduce depression symptoms and improve well-being without serious side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- psilocybin
- What this could lead to
- If it works, this could point toward a new way to ease severe depression in people with lung cancer, improving their quality of life.
- What could go wrong
- This is a very small, early-phase trial with only 10 participants, so results may not apply broadly. Psilocybin can cause hallucinations and emotional distress, and safety is still being checked.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
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