New radiation technique could boost immunotherapy in advanced lung cancer

NCT ID NCT06660407

First seen Mar 17, 2026 · Last updated Jun 23, 2026 · Updated 13 times

Summary

This study tests a special type of radiation called grid therapy, which delivers high doses to small parts of a tumor, combined with standard immunotherapy for people with stage IV non-small cell lung cancer that has stopped responding to treatment. About 20 adults will receive the combination to see if it is safe and helps shrink tumors. The goal is to improve outcomes without causing severe side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

grid radiation therapy

What this could lead to

If successful, this could offer a new treatment option for advanced lung cancer patients whose disease has worsened despite immunotherapy.

What could go wrong

This is a small early-phase trial with only 20 participants, so results may not apply broadly. There is a risk of side effects from the radiation and immunotherapy combination.

Conditions

The condition(s) this trial relates to.

lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.