LUNG NEOPLASMS

This early-stage study is testing a new type of personalized cell therapy for people with advanced solid tumors, including mesothelioma, that have come back or spread after standard treatments. Doctors collect a patient's own immune cells, genetically modify them in a lab to bett…

This study is testing whether the drug teniposide can help control advanced small cell lung cancer that has worsened despite standard chemotherapy. It is for patients whose cancer has a specific genetic feature called 'c-Myc-driven.' The main goal is to see if the drug shrinks tu…

This study is testing whether mobile low-dose CT scans can effectively detect lung cancer in younger, high-risk smokers. It focuses on people aged 40-54 with a heavy smoking history (30+ pack-years) in North and South Carolina. The goal is to see if starting screening earlier tha…

This study is testing a blood test as a first step before a CT scan for lung cancer screening. The goal is to see if the blood test can accurately identify people who are unlikely to have lung cancer, so they might avoid an unnecessary scan. This could reduce radiation exposure a…

This study is observing how well a robotic system works in real hospitals to help doctors locate and take samples from suspicious spots in the lungs. It will follow 3,000 patients who are already scheduled to have this robotic-assisted biopsy procedure. The main goal is to see ho…

This study is testing a telehealth coaching program designed specifically for Hispanic adults at high risk for lung cancer. Bilingual patient navigators help participants understand and decide about getting a low-dose CT scan for early cancer detection. The research aims to see i…

This study is testing whether a telehealth coaching program helps patients and their doctors make better, more informed decisions about lung cancer screening. It involves nearly 600 current or former heavy smokers aged 50-77. The goal is to see if coaching leads to more screening…

This study is testing if a steroid mouthwash can prevent painful mouth sores, a common side effect of a cancer drug called datopotamab deruxtecan. It will enroll 60 adults with advanced breast or lung cancer who are receiving this drug. The main goal is to see if using the mouthw…

This study aims to understand how doctors in Brazil treat advanced non-small cell lung cancer in real-world settings. Researchers will collect medical records from 200 patients and survey about 300 oncologists to see what treatments they choose and whether they follow national gu…

This study is creating a collection of tissue samples from people with lung cancer to support future research. Participants are those undergoing testing or treatment for lung cancer who consent to donate samples. The goal is to help scientists discover ways to detect lung cancer …

This study aims to learn why lung and other chest cancers sometimes stop responding to targeted treatments. Researchers will analyze tumor tissue from 500 adult patients to identify genetic changes linked to treatment resistance. The goal is to gather knowledge that could help do…

This study aims to develop a new, non-invasive way to monitor lung cancer patients after surgery to see if the cancer might come back. Researchers will collect blood samples from 100 patients who have had lung cancer surgery and analyze them using advanced computer programs. The …

This study aims to understand how lung cancer is treated and what it costs the healthcare system in Canada. Researchers will analyze existing health records from 60,000 patients in Alberta and Ontario to see what treatments were used, how long patients lived, and the associated h…

This study aims to create a detailed national picture of lung cancer in Algeria by observing patients in their normal care. It will track about 3,750 adults with lung cancer across 21 hospitals to understand their diagnosis, treatments, and health outcomes. The goal is to gather …

This study aims to see if cancer cells found in the blood (circulating tumor cells) can help doctors choose the right treatment for people with advanced lung cancer. Researchers will collect blood samples from 80 participants to grow these cells in the lab and test how they respo…