Blood test may cut unnecessary lung cancer scans in High-Risk groups
NCT ID NCT07358715
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a blood test (liquid biopsy) can be used as a first step to screen for lung cancer in high-risk people, before deciding if they need a low-dose CT scan. The goal is to reduce unnecessary scans, radiation exposure, and healthcare costs. The study will enroll 140 participants, including smokers and never-smokers with a family history of lung cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Liquid biopsy (SPOT-MAS assay and exosome-based assay)
- What this could lead to
- If successful, this blood test could help avoid unnecessary CT scans and radiation exposure for many people at high risk for lung cancer, making screening more efficient and affordable.
- What could go wrong
- This is a small, early feasibility study (140 participants). The blood test may not be accurate enough to replace CT scans, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National University Hospital Singapore
RECRUITINGSingapore, 119228, Singapore
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