HYPERTENSION (HTN)

This study tests whether trained female community health volunteers can effectively manage high blood pressure and diabetes in rural Nepal. About 400 adults with these conditions will receive health education, peer support, and monitoring from local volunteers, instead of relying…

This study collects information from 100 adults with high blood pressure who undergo a procedure called renal denervation, which uses radiofrequency or ultrasound to calm overactive kidney nerves. Researchers will measure blood pressure changes at home before and one year after t…

This study looks at how well CPAP therapy lowers blood pressure in people with obstructive sleep apnea and high blood pressure. It also tests whether adding a mild sleep medication (trazodone or zolpidem) for those with insomnia can boost the blood pressure benefits. About 200 ad…

This study aims to help people with uncontrolled high blood pressure (above 150/95) get their numbers down. It will involve about 1,520 adults across 56 primary care clinics in Ohio. The approach uses home blood pressure readings and a care team that includes pharmacists and adva…

This study looks at whether doing a simple isometric exercise (wall squats) at home, along with lifestyle advice, is a practical way for people with high blood pressure to manage their condition. Seventy adults with hypertension will do the exercises three times a week for 12 wee…

This study compares two types of exercise—short, intense bursts (SIT) versus steady, moderate activity (MICT)—to see which is better at lowering blood pressure in adults aged 30-59 with hypertension. Over 12 weeks, 20 participants will do supervised workouts three times a week. T…

This study compares a wearable blood pressure monitor (Aktiia G1) to a traditional arm cuff in people with high blood pressure. Over 6 months, researchers will see which method helps lower blood pressure better. Participants must have uncontrolled hypertension and own a smartphon…

This study tests whether adding a community health worker-led lifestyle program to remote blood pressure monitoring helps women who had high blood pressure during pregnancy. About 240 women will be followed for 6 months after delivery to see if the extra coaching improves blood p…

This study looks at whether adding a special breathing technique (alternate nostril breathing) to aerobic interval training helps lower blood pressure more than exercise alone. It includes 36 adults aged 25-50 with stage 1 or 2 hypertension. Participants will do supervised exerci…

This study compares two different drug combinations to see which works better for people with both high blood pressure and chronic kidney disease. About 30 adults will be randomly assigned to take either finerenone alone or a fixed-dose combination of torsemide and spironolactone…

This study checks if a small chest-patch that uses light to measure blood pressure works as well as the standard arm-cuff method over 24 hours. About 600 adults with or without high blood pressure will wear both devices. The goal is to see if the patch is accurate, easy to use, a…

This study looks at whether very short periods of exercise, like 5 to 10 minutes, can help lower blood pressure in people with hypertension or pre-hypertension. Researchers will measure blood pressure over 24 hours and check blood vessel health. The study needs 45 adults aged 18-…

This study looks at whether a beetroot supplement can help older women (ages 60-70) with high blood pressure during a single exercise session. Researchers will measure blood pressure, muscle oxygen levels, and markers of oxidative stress. The goal is to see if beetroot extract of…

This study tests whether adding transcutaneous electrical nerve stimulation (TENS) and isometric exercise to standard medication can improve blood pressure in people with resistant hypertension. Researchers will compare two groups of 25 adults aged 50-60: one doing TENS plus exer…

This study will use wearable digital health devices to collect heart data from 5,000 adults with chronic heart conditions like heart failure, high blood pressure, and aortic stenosis. The goal is to observe how these conditions progress over time. No new treatments or medications…

This study looks at whether two dietary supplements, Goodphyte IB Defense and Goodphyte Immunity, are easy for adults with chronic conditions like IBD, hypertension, multiple sclerosis, or anemia to take regularly. Researchers will also check if these supplements help the body ab…

This study is for adults recently diagnosed with high blood pressure. It checks if high levels of a substance called homocysteine in the blood are linked to early signs of heart stiffness. Researchers will use heart ultrasounds and other tests to compare patients with high and no…