HEALTHY ADULT

This study tests whether taking a probiotic supplement can help healthy Chinese adults maintain a balanced gut microbiome and feel better physically and mentally during a short trip to Europe. Forty participants will receive either the probiotic or a placebo for 7 days. The goal …

This study checks if a cream containing Mitopure is safe for the skin. Thirty healthy adults, half with sensitive skin, will apply the cream repeatedly for 2 weeks. Researchers will look for skin irritation and ask participants how they like the product.

This study tests a new robot-based therapy designed to improve arm movement and sensation in people who had a stroke more than six months ago. The therapy focuses on helping the brain better process sensory information. About 109 adults with chronic stroke will participate, and t…

This study looks at whether adding blood flow restriction (a technique that limits blood flow to the working muscle) to strength training is safe and effective. Sixty healthy adults will do an 8-week program of rotator cuff exercises at different intensities, with or without bloo…

This study explores whether a special ultrasound (shear wave elastography) can measure breathing effort by checking stiffness in chest muscles. Currently, doctors use a tube placed in the esophagus, which is uncomfortable. Researchers will test 20 people (some with COPD, some hea…

This study looks at how leg muscle strength relates to the ability to perform short, intense exercise in healthy, active men aged 20-30. Researchers will measure leg strength and anaerobic power in 80 participants using special equipment. The goal is to better understand how to d…

This early-stage study tests how food and a common heartburn drug (a proton pump inhibitor) change the way the body absorbs a new experimental drug called VRN101099. Twenty-four healthy adults will take the drug under different conditions to measure blood levels and safety. The r…

This study looks at how the brain naturally reduces pain in healthy adults. Researchers will use mild heat and pressure to trigger the body's pain-inhibiting pathway, and brain stimulation (TMS) to measure brain activity. The goal is to understand how factors like stress and opti…

This early-stage trial tests the safety and tolerability of a new drug, CIT-013, in 10 healthy adults. Participants receive either the drug or a placebo to see how the body handles it. The study aims to gather initial safety data before testing in patients with a disease.

This study looks at whether exercise reduces pain sensitivity differently in men and women. Thirty healthy adults will do a cycling workout, and their pain thresholds will be measured before, right after, and 30 minutes after exercise. The goal is to help create personalized exer…

This study aims to improve how doctors predict which heart failure patients will respond to a treatment called cardiac resynchronization therapy (CRT), which uses a special pacemaker to coordinate heartbeats. Currently, about 30% of patients do not get better with CRT. Researcher…

This early-phase trial will give a single inhaled dose of an experimental drug called GH001 to 12 healthy adults. Researchers will measure how the drug moves through the body and check for any side effects. The goal is to gather safety and dosing information, not to treat any dis…

This study tests whether a digital game can improve how midwifery students learn about preeclampsia and eclampsia—serious pregnancy complications. About 120 fourth-year students will be split into three groups: digital game, simulation, or traditional lecture. Their knowledge and…

This study looks at whether offering genetic testing for alcohol flushing, along with education, is practical and helpful for East Asian American adults. About 100 people who experience flushing when drinking or have a family history of it will take part. Half will get education …

This study looks at how non-invasive brain stimulation (rTMS) affects two different areas of the cerebellum—one linked to movement and one linked to thinking. Forty healthy adults will receive either stimulating, inhibiting, or fake (placebo) stimulation in random order. The goal…

This early-stage study tests a new drug called DW5524 in 48 healthy adults to see if it is safe and how the body processes it. Participants receive a single dose and are monitored for side effects and drug levels. The study is not yet recruiting and does not aim to treat any dise…

This study compares foam rolling and massage to see which reduces calf muscle tension more in healthy adults. Researchers will measure muscle tone, stiffness, and elasticity before and after each technique. The goal is to understand if a simple foam roller can work as well as a p…

This study looks at how urolithin A, a compound from the supplement Mitopure®, moves into the fluid around the brain and spinal cord. Researchers will give the supplement to 40 healthy adults aged 18 to 45 and measure levels in their blood and spinal fluid at different times. The…

This early-stage study tests whether a new liposome formula is safe in 12 healthy adults aged 18 to 30. Researchers will monitor side effects and measure how the drug moves through the body. No treatment is given—the goal is to gather safety information for future studies.