Heart rate drug may reveal why exercise gets harder with age
NCT ID NCT07717710
First seen Jul 21, 2026 · Last updated Jul 23, 2026 · Updated 2 times
Summary
This study tests whether ivabradine, a medication that slows heart rate without weakening the heart's pumping strength, can help researchers understand how heart rate limits exercise capacity. Healthy younger and older adults will take a single dose of ivabradine before cycling tests to measure heart rate and work rate. The goal is to learn why the heart's ability to pump blood plateaus during exercise, which may explain age-related declines in exercise tolerance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ivabradine (a heart-rate-lowering medication)
- What this could lead to
- If successful, this study could clarify how heart rate affects the heart's ability to supply oxygen during exercise, potentially informing treatments for age-related exercise limitations.
- What could go wrong
- This is a small, early-phase pilot study in healthy volunteers, so results may not apply to people with heart conditions. Side effects like slow heart rate, visual symptoms, and headache are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEALTHY ADULT are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
SportsCardiologyBC, UBC Hospital
Vancouver, British Columbia, V6T 2B5, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a better hazmat suit keep first responders safer and more effective?
- Home video tracking may expose the gap between clinic walking and real-world walking after stroke
- Avocado at breakfast: a secret weapon for blood sugar and fullness?
- Hamstring showdown: eccentric lifts vs sprinting for muscle gains
- Could a simple questionnaire replace the gold standard for measuring salt intake?
- Can a chromium supplement tame blood sugar before problems start?