Can magnetic brain zaps ease the pain of a sleepless body?
NCT ID NCT07827677
First seen Sep 18, 2026 · Last updated Sep 18, 2026
Summary
People with insomnia often feel pain more intensely and recover from muscle strain more slowly. This pilot trial tests whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive technique that alters brain activity, can reduce pain sensitivity and speed recovery after a standard muscle-soreness exercise. Thirty adults with insomnia receive either real rTMS aimed at one of two brain regions or a sham version, then researchers track pain thresholds and soreness over several days.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- repetitive transcranial magnetic stimulation (rTMS) delivered to two different brain targets
- What this could lead to
- If it works, this could point toward a non-invasive brain-stimulation option for easing muscle pain and speeding recovery in people who sleep poorly.
- What could go wrong
- This is a small pilot study of 30 people using an experimental muscle-soreness model, so any benefit may not hold up in real-world pain or in larger trials. rTMS can cause scalp discomfort, headache, or, rarely, seizure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 60 years * Right hand and foot dominant Exclusion Criteria: * History of any chronic musculoskeletal pain or presence of existing pain during recruitment * Previous major injuries or surgery involving the lower limbs * Sleep disorders other than insomnia * Clinically diagnosed psychiatric disorders * Conditions that preclude safe rTMS or pain testing (e.g., severe head trauma, intracranial hypertension, implanted ferromagnetic devices, history of epilepsy, skin conditions at stimulation sites) * Contraindications to vigorous exercise identified through the physical activity readiness questionnaire (PAR-Q) * Work night shifts or rotating shift schedules * Pregnant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Hong Kong Polytechnic University
RECRUITINGHong Kong, Hong Kong
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