DYSLIPIDEMIAS

This study tested a single pill containing three medicines (telmisartan, amlodipine, and rosuvastatin) in 252 Korean adults with both high blood pressure and high cholesterol. After 8 weeks, the pill lowered blood pressure and LDL (bad) cholesterol. The goal was to see if combini…

This study tested a new extended-release tablet called K-877 in 121 adults with high triglycerides (a type of blood fat). Participants took the pill once daily for 52 weeks, either in the morning or evening. The goal was to see if the drug safely lowers triglyceride levels over t…

This early-stage study tested a new medicine called ARO-ANG3 in 93 healthy adults and people with high cholesterol or high triglycerides. The main goal was to see if the drug is safe and how the body processes it. This is a first step toward a possible new treatment for lipid dis…

This study looked at whether a three-month supervised exercise program can help men with type 2 diabetes, prediabetes, or obesity improve their blood sugar, body composition, and fitness. Three hundred sedentary men aged 35-65 took part in regular training sessions at a fitness c…

This study looked at whether taking a natural plant supplement called phytosterol can help people with nonalcoholic fatty liver disease (NAFLD). 27 adults took the supplement for 3 months. Researchers measured changes in liver enzymes, cholesterol, insulin, and inflammation. The …

This study tested whether a low dose (10 mg) of the statin drug rosuvastatin works well in Korean adults who need cholesterol-lowering therapy. It included 242 people with high cholesterol, diabetes, or prior heart problems. The main goal was to see how much their LDL (bad) chole…

This study tested a medication called Cipros 20 in 406 adults with dyslipidemia (abnormal fat levels in the blood) who also had high or very high heart disease risk. The goal was to see if the drug could lower triglycerides and LDL (bad) cholesterol more effectively than existing…

This study tested a new drug called obicetrapib in over 2,500 adults with very high cholesterol or heart disease whose cholesterol was not well-controlled by their current medications. Participants took either the study drug or a placebo pill daily for about 6 months. The main go…

This study looked at how eating different amounts of pecans each day for 28 days affects heart health in 108 adults who are overweight or have high cholesterol. Participants ate pecans as part of their diet or stuck to their usual eating habits. Researchers measured changes in bl…

This phase 3 study tested a daily pill that combines two drugs, obicetrapib and ezetimibe, to lower LDL (bad) cholesterol in 407 adults with inherited high cholesterol (HeFH) or heart disease (ASCVD). Participants were already on maximum cholesterol-lowering therapy. The main goa…

This study tested a new controlled-release version of the drug pemafibrate in 60 adults with dyslipidemia (abnormal fat levels in the blood). The goal was to see if the new pill works better or has fewer side effects than the current version. Participants took both versions at di…

This study tested a drug called alirocumab in 118 adults with HIV who were at risk for heart disease. The goal was to see if the drug could reduce inflammation in the arteries and improve blood vessel function. Participants received either the drug or a placebo for about a year, …

This study tested a digital quality improvement program to help doctors better manage LDL (bad) cholesterol in patients with heart disease. Over 1,400 adults in Brazil with established cardiovascular disease participated. The program used smartphone tools to improve treatment and…

This study looked at whether taking fish oil supplements while exercising can lower inflammation linked to obesity. Overweight adults with high triglycerides and prediabetes took fish oil and followed an exercise program for several weeks. Researchers measured changes in blood ma…

This study looked at whether drinking Dachundou No Sugar Added Soymilk every day for 8 weeks can lower cholesterol in adults with high cholesterol. 25 participants drank two bottles of soymilk daily. Researchers measured cholesterol, blood pressure, and other health markers. The …

This study looked at the long-term safety of a drug called ARO-APOC3 in adults with dyslipidemia (abnormal fat levels in the blood). 418 people who completed a previous 12-month study received the drug every 3 to 6 months. The main goal was to check for side effects over time.

This study looked at whether smaller amounts of cottonseed oil can improve cholesterol and other health markers in adults at risk for heart disease. 95 overweight or at-risk adults drank shakes with different doses of cottonseed oil daily for 28 days. Researchers measured changes…

This pilot study tested a quality improvement process to help staff at mental health clinics deliver better care for heart disease risk factors like diabetes, high blood pressure, and high cholesterol. Researchers worked with 85 participants, including clinic staff and people wit…

This study tested whether a personalized lifestyle program could help people with obesity and related conditions like prediabetes or high blood pressure improve their insulin resistance. Forty adults received either nutrition or exercise counseling first, and if they didn't impro…

This study looked at how taking statins (cholesterol-lowering pills) along with a 12-week exercise program affects muscle cells and overall fitness in adults aged 40-65 with high cholesterol. 120 participants were split into four groups: exercise plus placebo, exercise plus stati…

This early-phase study tested the safety and how the body processes Atorvo+™ in 24 healthy adults aged 40 to 75. Participants received either the study drug or a placebo to check for side effects and measure drug levels in the blood. The goal was to gather safety information, not…

This early-stage study tested a single dose of VSA003 in 36 healthy Chinese adults to see if it is safe and how the body processes it. Participants had slightly high cholesterol or triglycerides. The goal was not to treat disease but to gather safety and drug-level data before mo…