New Once-Daily pill aims to lower high triglycerides

NCT ID NCT04716595

Completed Disease control Sponsor: Kowa Company, Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new extended-release form of pemafibrate (K-877) in 121 adults with high triglycerides, a type of fat in the blood. Participants took the drug once daily for 52 weeks, either in the morning or evening, to see if it safely lowers triglyceride levels and improves cholesterol. The goal is to offer a convenient treatment option for managing dyslipidemia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pemafibrate (K-877) extended-release tablet
What this could lead to: If successful, this could provide a once-daily treatment option to lower high triglycerides and improve cholesterol levels, helping manage heart disease risk.
What could go wrong: This is a completed Phase 3 trial, but results are not yet published. The drug may not work better than existing treatments, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Dyslipidemias hyperlipidemia inherited lipid metabolism disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DYSLIPIDEMIAS

Contacts and locations

Locations

Akasaka Chuou Clinic

Tokyo, Japan
Cosmos medical corporation Aozora total clinic

Saitama, Japan
Hasegawa Medicine Clinic

Hokkaido, Japan
Japan Community Health care Organization Hokkaido Hospital

Hokkaido, Japan
Kinugawa Cardiology Clinic

Osaka, Japan
Kyosokai AMC NISHI-UMEDA Clinic

Osaka, Japan
Medical Corporation Chiseikai Tokyo Center Clinic

Tokyo, Japan
Medical corporation Tani clinic

Osaka, Japan
Minami Akatsuka Clinic

Ibaraki, Japan
National Hospital Organization Takasaki General Medical Center

Gunma, Japan
Saiseikai Futsukaichi Hospital

Fukuoka, Japan
Saiseikai Yokohamashi Nanbu Hospital

Kanagawa, Japan
Shimokitazawa Tomo Clinic

Tokyo, Japan
Shiraiwa medical clinic

Osaka, Japan

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