DRUG RESISTANT EPILEPSY

This pilot study tests whether repeated sessions of low-intensity focused ultrasound can safely reduce seizures in people with drug-resistant temporal lobe epilepsy. Ten adults who still have seizures despite trying at least two medications will receive the ultrasound treatment. …

This study tests a non-invasive brain stimulation technique called tDCS in 60 people with epilepsy that doesn't respond to medication. Participants will receive either real or sham (fake) stimulation for 10 days to see if it safely reduces seizure frequency. The goal is to improv…

This study tests whether focused ultrasound can safely reduce seizures in 20 adults whose epilepsy does not respond to medication. Participants receive ultrasound waves to specific brain areas, and researchers monitor seizure frequency, brain activity, and side effects. The goal …

This study follows 100 children under 18 who are already using a ketogenic diet for conditions like drug-resistant epilepsy, autism, chronic migraine, or brain tumors. Researchers want to see if the diet supports healthy growth, improves symptoms, and boosts quality of life over …

This study tests a tablet-based tool called the Epilepsy Visit Planner for adults with drug-resistant epilepsy. The tool helps patients share their goals and concerns with their doctor during clinic visits. Researchers want to see if it improves communication and quality of life …

This study tests a new, non-invasive treatment for people with epilepsy that doesn't respond to medication. The treatment uses infrared light, which has shown promise in animal studies. Researchers want to see if daily light therapy can reduce the number and length of seizures, a…

This early study tests a new, non-invasive treatment for people with temporal lobe epilepsy that doesn't respond to medication. It uses low-intensity focused ultrasound to calm overactive brain areas. The main goal is to see if the treatment is safe and tolerable, and to check if…

This study tests a device called NaviFUS™ that uses low-intensity focused ultrasound to calm overactive brain areas causing seizures. It is for adults with epilepsy that does not respond to medication. The goal is to see if this treatment can safely reduce seizure frequency. Sixt…

This study uses PET and MRI scans to look at serotonin pathways in the brainstem of adults with Dravet syndrome, a severe form of epilepsy. Researchers want to see if these pathways are different in Dravet patients compared to those with other drug-resistant epilepsy and healthy …

This study compares two advanced brain-mapping techniques—MEG and high-resolution EEG—to see which better pinpoints the exact area causing seizures in people with drug-resistant epilepsy who are candidates for surgery. One hundred participants will undergo both scans before their…

This study is collecting information from 4,500 people who have had brain surgery for conditions like aneurysms, tumors, or epilepsy. The goal is to find out what factors help predict recovery, such as thinking skills and emotional health. By standardizing how outcomes are measur…

This study looks at how seizures change the brain's wiring in children with hard-to-control focal epilepsy. Researchers will use special brain recordings and MRI scans to measure connections in areas where seizures start. The goal is to understand how ongoing seizure activity aff…

This study looks at how the bacteria in your gut might affect epilepsy that doesn't get better with standard medicines. Researchers will follow 120 people aged 3 to 50 who have drug-resistant epilepsy and are starting a new treatment like surgery or a special diet. By tracking ch…