DRUG RESISTANT EPILEPSY

This study tests whether a fluorescent dye called 5-ALA can help surgeons see and remove abnormal brain tissue in people with drug-resistant epilepsy caused by focal cortical dysplasia (FCD). FCD lesions are often hard to distinguish from healthy brain during surgery, making comp…

This study tests whether cannabis-based treatments can safely reduce seizures in people aged 2 to 55 with drug-resistant epilepsy. Participants will receive either a pure CBD extract, a CBD-rich herbal cannabis extract, or a placebo. The goal is to see if these treatments lower m…

This study looks at whether a non-invasive technique called focused ultrasound can safely treat brain lesions that cause seizures in children with drug-resistant epilepsy. About 20 children aged 4-17 will be followed to see if the treatment reduces seizure frequency and severity,…

This study tests a non-invasive brain training technique called neurofeedback for people with drug-resistant epilepsy. Participants learn to change their own brain activity to reduce seizures. The study compares real neurofeedback to a sham (fake) version to see if it truly works…

This study will test whether a modified Atkins diet can help children aged 1-18 with drug-resistant epilepsy. Researchers will track seizure control, quality of life, thinking skills, and growth in 40 children who follow the diet for at least 6 months. The goal is to see if this …

This study tests whether a non-invasive brain stimulation technique called temporal interference (TI) can reduce abnormal brain activity and improve sleep in adults with drug-resistant temporal lobe epilepsy. Twenty participants will stay in a sleep lab for six nights, receiving …

This study will collect real-world data from 100 people with drug-resistant epilepsy who receive or are considered for a procedure using the OneRF Ablation System. The system uses radiofrequency energy to target and destroy small areas of brain tissue causing seizures. Researcher…