Could a night of brain zapping improve sleep and seizures in epilepsy?
NCT ID NCT07434986
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a non-invasive brain stimulation technique called temporal interference (TI) can reduce abnormal brain activity and improve sleep in adults with drug-resistant temporal lobe epilepsy. Twenty participants will stay in a sleep lab for six nights, receiving TI stimulation during sleep on some nights and no stimulation on others. Researchers will compare seizure-related brain activity and sleep quality between these nights to see if the stimulation helps.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Non-invasive temporal interference (TI) electrical stimulation
What this could lead to
If it works, this could point toward a non-invasive way to reduce seizure-related brain activity and improve sleep for people with drug-resistant epilepsy.
What could go wrong
This is a very small early study with only 20 participants, so results may not apply to everyone. The stimulation may not reduce seizure activity or improve sleep, and side effects are not yet well understood.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Anphy Lab - Inside Hock Plaza
Durham, North Carolina, 27705, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••