Sound waves aimed at the brain could tame seizures
NCT ID NCT06388707
First seen Apr 14, 2026 · Last updated Jun 22, 2026 · Updated 11 times
Summary
This early study tests a device that uses low-intensity focused ultrasound to calm overactive brain areas in people with drug-resistant temporal lobe epilepsy. Eight adults will receive up to three 10-minute ultrasound sessions. Researchers will track side effects and check if seizure frequency changes. The goal is to see if this non-invasive approach is safe and worth studying further.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact
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Stanford University School of Medicine
RECRUITINGPalo Alto, California, 94305, United States
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University of Virginia School of Medicine
RECRUITINGCharlottesville, Virginia, 22903, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
low-intensity focused ultrasound (LIFU) device
What this could lead to
If it works, this could point toward a non-invasive treatment option for people with drug-resistant epilepsy, potentially reducing seizure frequency without surgery.
What could go wrong
This is a very small, early pilot study with only 8 participants, so results may not apply widely. The treatment is still experimental, and safety and effectiveness are not yet proven.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.