Sound waves aimed at the brain could tame epilepsy seizures

NCT ID NCT03868293

Recruiting now Symptom relief Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot trial tests whether repeated sessions of pulsed low-intensity focused ultrasound can safely reduce seizures in people with drug-resistant temporal lobe epilepsy. Ten adults who still have seizures despite medication will receive the ultrasound treatment. Researchers will check for side effects and measure changes in seizure frequency and brain activity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pulsed low-intensity focused ultrasound (device)
What this could lead to: If it works, this could point toward a non-invasive treatment to reduce seizures in people with drug-resistant epilepsy.
What could go wrong: This is a very small pilot study with only 10 participants, so results may not apply widely. The treatment may not reduce seizures or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy temporal lobe epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRUG-RESISTANT EPILEPSY

Contacts and locations

Locations

Brigham and women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

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