Sound waves vs. seizures: new ultrasound trial for Hard-to-Treat epilepsy
NCT ID NCT06292494
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether focused ultrasound can safely reduce seizures in people with drug-resistant epilepsy. Twenty adults who have not responded to at least two seizure medications will receive ultrasound treatment to interrupt brain circuits causing seizures. Researchers will monitor seizure frequency, brain activity, and side effects to see if this non-invasive approach works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- focused ultrasound (Exablate 4000 device)
- What this could lead to
- If it works, this could offer a non-invasive way to reduce or stop seizures in people with drug-resistant epilepsy, potentially reducing the need for medications.
- What could go wrong
- This is a small early-phase study with only 20 participants, so results may not apply widely. The treatment may not work for everyone, and there are risks like temporary side effects from the ultrasound.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Taipei Veterans General Hospital
RECRUITINGTaipei, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a High-Fat diet and therapy tame seizures in rare childhood epilepsy?
- Zapping the brain without surgery: a new hope for Tough-to-Treat epilepsy
- Nerve block may cut opioid needs after epilepsy device surgery
- Sound waves aimed at the brain could quiet seizures
- Glowing dye could help surgeons spot hidden epilepsy lesions
- Brain scans may replace invasive electrodes for epilepsy surgery planning