Sound waves vs. seizures: new ultrasound trial for Hard-to-Treat epilepsy

NCT ID NCT06292494

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether focused ultrasound can safely reduce seizures in people with drug-resistant epilepsy. Twenty adults who have not responded to at least two seizure medications will receive ultrasound treatment to interrupt brain circuits causing seizures. Researchers will monitor seizure frequency, brain activity, and side effects to see if this non-invasive approach works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

focused ultrasound (Exablate 4000 device)

What this could lead to

If it works, this could offer a non-invasive way to reduce or stop seizures in people with drug-resistant epilepsy, potentially reducing the need for medications.

What could go wrong

This is a small early-phase study with only 20 participants, so results may not apply widely. The treatment may not work for everyone, and there are risks like temporary side effects from the ultrasound.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Taipei Veterans General Hospital

    RECRUITING

    Taipei, Taiwan

    Contact Email: •••••@•••••