AORTIC STENOSIS
Clinical trials for AORTIC STENOSIS explained in plain language.
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New heart procedure may reduce stroke risk without blood thinners
Disease control CompletedThis study tested a procedure called left atrial appendage occlusion (LAAO) against standard blood-thinning medications in 81 people with atrial fibrillation who were getting a new heart valve (TAVI). The goal was to see if LAAO could prevent strokes and bleeding better than drug…
Matched conditions: AORTIC STENOSIS
Phase: NA • Sponsor: University of Zurich • Aim: Disease control
Last updated May 17, 2026 05:45 UTC
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New device may prevent blocked arteries during heart valve re-do
Disease control CompletedThis study tested a device called ShortCut in 8 people who needed a second valve replacement inside a failing artificial heart valve. The device splits the old valve leaflets to keep them from blocking the coronary arteries during the new valve placement. The goal was to see if t…
Matched conditions: AORTIC STENOSIS
Phase: NA • Sponsor: Pi-cardia • Aim: Disease control
Last updated May 17, 2026 05:44 UTC
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New heart valve technology passes safety check in large study
Disease control CompletedThis study looked at a new way of treating heart valves before they are implanted in people who need a replacement for their aortic or mitral valve. The goal was to make sure the new process is safe and works as well as current methods. Over 700 adults took part, and researchers …
Matched conditions: AORTIC STENOSIS
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 17, 2026 05:36 UTC
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New heart valve offers hope for High-Risk chinese patients
Disease control CompletedThis study tested the safety and effectiveness of the SAPIEN 3 heart valve in 58 Chinese patients with severe aortic stenosis who were at high risk for open-heart surgery. The valve was implanted using a less invasive procedure called TAVI. The main goal was to see how many patie…
Matched conditions: AORTIC STENOSIS
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 17, 2026 05:30 UTC
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Can a gout drug slow heart valve disease?
Disease control CompletedThis study tested whether colchicine, an anti-inflammatory drug, can slow the buildup of calcium in the aortic valve in people with mild-to-moderate aortic stenosis. 24 adults were randomly assigned to take colchicine or a placebo for 6 months. The main goal was to see if the dru…
Matched conditions: AORTIC STENOSIS
Phase: PHASE2, PHASE3 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New heart valves show promise for indian patients with severe aortic stenosis
Disease control CompletedThis study tested two new heart valves (Portico and Navitor) in 30 Indian patients with severe aortic stenosis who were at high risk for surgery. The goal was to see if the valves were safe and worked well. Researchers tracked complications like death, stroke, and bleeding for up…
Matched conditions: AORTIC STENOSIS
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 06, 2026 16:03 UTC
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Heart valve fix may boost brain power in seniors
Knowledge-focused CompletedThis study looked at 81 people with mild memory problems who were getting a heart valve replacement (TAVR). Researchers tested their thinking and memory before and after the procedure using a 5-minute quiz. The goal was to see if fixing the heart valve helps improve brain functio…
Matched conditions: AORTIC STENOSIS
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 05:43 UTC
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Heart valve study aims to sharpen artery blockage tests
Knowledge-focused CompletedThis study looked at 116 people with severe aortic stenosis (a narrowed heart valve) and moderate coronary artery blockages. Researchers measured blood flow in the heart arteries before, right after, and 6 months after valve replacement surgery or a less invasive procedure. The g…
Matched conditions: AORTIC STENOSIS
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated May 15, 2026 12:01 UTC