New device aims to prevent deadly blockage during heart valve replacement

NCT ID NCT05666713

First seen Feb 03, 2026 · Last updated May 13, 2026 · Updated 11 times

Summary

This study tested a new tool called TELLTALE designed to make heart valve replacement safer. In 90 adults at high risk of a serious complication where a heart flap blocks blood flow, doctors used the device to cut the flap during the procedure. The goal was to see if the tool works well and reduces risks like stroke or death.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • California Pacific Med Ctr

    San Francisco, California, 94109, United States

  • Carilion Medical Center

    Roanoke, Virginia, 24014, United States

  • Emory University

    Atlanta, Georgia, 30308, United States

  • Medstar WHC

    Washington D.C., District of Columbia, 20010, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Rochester Regional Health

    Rochester, New York, 14621, United States

  • St. Francis Hospital and Heart Center

    Roslyn, New York, 11576, United States

  • University of Colorado Health

    Fort Collins, Colorado, 80528, United States

  • University of Washington Heart Institute

    Seattle, Washington, 98195, United States

Conditions

Explore the condition pages connected to this study.