New device aims to prevent blocked arteries during repeat heart valve surgery

NCT ID NCT06211296

Completed Disease control Sponsor: Pi-cardia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a device called ShortCut that splits the leaflets of a failing artificial heart valve before placing a new valve inside it. The goal was to prevent the old leaflets from blocking the coronary arteries, which can cause a heart attack. Eight people at risk for this complication took part, and researchers measured how well the device split the leaflets and whether it caused death or stroke.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ShortCut device (splits bioprosthetic aortic valve leaflets)
What this could lead to: If successful, this device could help prevent serious complications like heart attack or stroke during valve-in-valve procedures for people with failing artificial heart valves.
What could go wrong: This was a very small study (8 people) with no comparison group, so results may not apply widely. The device itself carries risks of death or stroke.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis Bites and Stings coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC STENOSIS CORONARY; OBSTRUCTION VALVE-IN-VALVE PROCEDURES

Contacts and locations

Locations

Columbia University Medical Center /NYPH

New York, New York, 10032, United States
Los Robles Regional Medical Center

Thousand Oaks, California, 91360, United States
Morristown Medical Center

Morristown, New Jersey, 07960, United States
UPMC Pinnacle

Wormleysburg, Pennsylvania, 17043, United States

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