New heart valve offers hope for High-Risk chinese patients

NCT ID NCT03466918

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a new heart valve, the SAPIEN 3, in 58 Chinese patients with severe aortic stenosis who were at high risk for traditional open-heart surgery. The valve was implanted using a thin tube through a blood vessel, avoiding the need for open surgery. The main goal was to see how many patients survived and how safe the procedure was.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SAPIEN 3 transcatheter heart valve

What this could lead to

If successful, this could provide a less invasive treatment option for Chinese patients with severe aortic stenosis who are too high-risk for open-heart surgery.

What could go wrong

This was a small, single-arm study (58 participants) with no comparison group, so results may not apply broadly. Risks include stroke, bleeding, or valve-related complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve insufficiency aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fuwai Hospital, CAMS&PUMC

    Beijing, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, China

  • WestChina Hospital, Sichuan University

    Chengdu, China

  • Zhongshan Hospital Fudan University

    Shanghai, China