AORTIC REGURGITATION
Clinical trials for AORTIC REGURGITATION explained in plain language.
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Heart valve showdown: Less-Invasive procedure vs. open surgery
Disease control Recruiting nowThis large study aims to find out which of two procedures is better for treating severe aortic regurgitation, a condition where a heart valve leaks. It will compare a newer, less-invasive procedure (TAVR) with traditional open-heart surgery (SAVR) in 1,250 patients aged 65 and ol…
Matched conditions: AORTIC REGURGITATION
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New heart valve procedure tested for leaky valve patients
Disease control Recruiting nowThis study is testing a minimally invasive procedure to replace a leaky heart valve (aortic regurgitation) in patients aged 60 and older. It compares a specific new valve system (VitaFlow Liberty) against other approved devices to see which is safer and more effective at preventi…
Matched conditions: AORTIC REGURGITATION
Phase: PHASE4 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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New hope for heart pump patients with failing valves
Disease control Recruiting nowThis study is testing a new, less invasive heart valve replacement procedure for patients who have mechanical heart pumps (LVADs) and develop leaky aortic valves. The procedure uses a device called the JenaValve Trilogy system, which is inserted through blood vessels without open…
Matched conditions: AORTIC REGURGITATION
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Pioneering trial tests less invasive fix for leaky heart valves
Disease control Recruiting nowThis study aims to see if a new, less invasive procedure to replace a leaky aortic heart valve is as safe and effective as traditional open-heart surgery. It will involve over 1,000 patients with significant aortic regurgitation, where blood leaks backward into the heart. Researc…
Matched conditions: AORTIC REGURGITATION
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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Doctors test which heart scan is best for valve problems
Knowledge-focused Recruiting nowThis study aims to compare different types of heart scans to see which ones most accurately measure the severity of valve disease and heart muscle health. Researchers will enroll 200 adults with moderate or severe aortic or mitral valve problems. They will compare standard ultras…
Matched conditions: AORTIC REGURGITATION
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Apr 01, 2026 22:56 UTC
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Heart scans reveal hidden gender gaps in valve disease
Knowledge-focused Recruiting nowThis study aims to understand how heart valve disease affects men and women differently using advanced heart scans. Researchers will analyze detailed heart images from 200 adults with moderate to severe valve problems to identify patterns that might explain why women often have w…
Matched conditions: AORTIC REGURGITATION
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC