AORTIC REGURGITATION
Clinical trials for AORTIC REGURGITATION explained in plain language.
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New heart valve procedure could offer a gentler option for leaky valve patients
Disease control Recruiting nowThis study tests a new, less invasive way to replace a leaky aortic heart valve (aortic regurgitation) using a device called the JenaValve Trilogy, compared to standard open-heart surgery. About 1,000 people with moderate to severe aortic regurgitation will be randomly assigned t…
Matched conditions: AORTIC REGURGITATION
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New heart valve device could help patients with heart pumps avoid open surgery
Disease control Recruiting nowThis study is testing a new heart valve device (JenaValve Trilogy) placed through a tube in an artery, without open surgery. It is for 50 adults who have a mechanical heart pump (LVAD) and also a leaky aortic valve that makes the pump work less effectively. The goal is to see if …
Matched conditions: AORTIC REGURGITATION
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New heart valve procedure could offer safer alternative to Open-Heart surgery for seniors
Disease control Recruiting nowThis study tests whether a newer, less invasive procedure called transcatheter aortic valve replacement (TAVR) using the J-VALVE device is as safe and effective as traditional open-heart surgery for people with severe aortic regurgitation (a leaky heart valve). About 1,250 adults…
Matched conditions: AORTIC REGURGITATION
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New heart valve procedure could help patients with leaky aortic valve
Disease control Recruiting nowThis study tests a new way to replace the aortic valve in people with severe aortic regurgitation (a leaky heart valve). About 180 patients will get either the new VitaFlow valve or another device through a tube in the leg. The goal is to see if the new valve is safe and effectiv…
Matched conditions: AORTIC REGURGITATION
Phase: PHASE4 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Can MRI beat ultrasound for heart valve diagnosis?
Diagnosis Recruiting nowThis study compares two heart imaging methods—echocardiography (ultrasound) and cardiac MRI—to see which measures heart valve disease more accurately. Researchers will enroll 200 adults with suspected moderate or severe valve problems. The goal is to improve how doctors assess va…
Matched conditions: AORTIC REGURGITATION
Sponsor: The Cleveland Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 08:10 UTC
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AI boosts heart valve diagnosis speed and accuracy
Knowledge-focused Recruiting nowThis study tests whether artificial intelligence (AI) can help cardiologists read echocardiograms (heart ultrasounds) more quickly and consistently. Researchers will give AI analysis to doctors in real time as they review heart images from 50 participants with valve disease. The …
Matched conditions: AORTIC REGURGITATION
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Heart valve disease: could Sex-Specific MRI scans predict better outcomes?
Knowledge-focused Recruiting nowThis study aims to find biological differences between men and women with heart valve disease using advanced MRI techniques. Researchers will enroll 200 adults with moderate to severe aortic or mitral valve problems. The goal is to better predict how the heart recovers after valv…
Matched conditions: AORTIC REGURGITATION
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC