AORTIC REGURGITATION
Clinical trials for AORTIC REGURGITATION explained in plain language.
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New heart valve fix without open surgery could change care for leaky aortic valve patients
Disease control Recruiting nowThis study compares a newer, less invasive procedure called transcatheter aortic valve replacement (TAVR) using the J-VALVE system to traditional open-heart surgery for people with severe aortic regurgitation (a leaky heart valve). About 1,250 adults aged 65 and older with sympto…
Matched conditions: AORTIC REGURGITATION
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New heart valve procedure could replace Open-Heart surgery for leaky valve patients
Disease control Recruiting nowThis study tests a new, less invasive way to replace a leaky aortic heart valve (aortic regurgitation) using a device called the JenaValve Trilogy system. It will compare this approach to standard open-heart surgery in about 1,016 people. The main goals are to see if the new meth…
Matched conditions: AORTIC REGURGITATION
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated May 11, 2026 20:47 UTC
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New heart valve procedure could offer hope for patients with leaky aortic valve
Disease control Recruiting nowThis study is testing a new way to fix a leaky heart valve (aortic regurgitation) without open-heart surgery. About 180 people with moderate-to-severe aortic regurgitation will receive a new valve system called VitaFlow Liberty through a tube in the leg. The goal is to see if thi…
Matched conditions: AORTIC REGURGITATION
Phase: PHASE4 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated May 04, 2026 16:22 UTC
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New valve trial offers hope for heart pump patients with leaky valve
Disease control Recruiting nowThis study tests a new heart valve (JenaValve Trilogy) placed without open-heart surgery in 50 adults who have a left ventricular assist device (LVAD) and a leaky aortic valve. The goal is to see if the valve is safe and works well to improve blood flow and reduce complications. …
Matched conditions: AORTIC REGURGITATION
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Heart imaging showdown: echo vs MRI in valve disease study
Knowledge-focused Recruiting nowThis study aims to see how well different heart ultrasound methods (2D and 3D echocardiography) compare to cardiac MRI for measuring heart function and valve problems. Researchers will enroll 200 adults with suspected moderate to severe heart valve disease. The goal is to improve…
Matched conditions: AORTIC REGURGITATION
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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AI boosts heart scan reading speed and consistency
Knowledge-focused Recruiting nowThis study tests whether artificial intelligence (AI) can help heart doctors read echocardiograms (heart ultrasounds) more quickly and consistently. Researchers will give AI analysis to cardiologists in real time as they review scans for valve disease. The goal is to see if AI re…
Matched conditions: AORTIC REGURGITATION
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Heart valve disease: new MRI study seeks Sex-Specific clues for better treatment
Knowledge-focused Recruiting nowThis study aims to identify biological differences between men and women with heart valve disease (aortic regurgitation, mitral regurgitation, or aortic stenosis) using advanced MRI techniques. Researchers will enroll 200 adults with moderate to severe valve disease to develop se…
Matched conditions: AORTIC REGURGITATION
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC