ANEMIA

This study tests whether adding digital nutrition education—via SMS or group sessions—to daily micronutrient supplements can lower anemia rates in 1,200 adolescents aged 15-19 in Dar es Salaam, Tanzania. All participants get supplements and basic nutrition info; some also receive…

This trial tests an experimental oral drug, ofirnoflast, in adults with lower-risk myelodysplastic syndromes (MDS) who have anemia and need regular red blood cell transfusions. The goal is to see if the drug can reduce or eliminate transfusion needs and improve blood counts. Part…

This phase 2 trial tests whether spironolactone, a drug usually used for heart failure and high blood pressure, can help treat anemia in children aged 6–18 who are on hemodialysis. Participants take spironolactone daily for 12 weeks alongside standard care, and researchers measur…

This study compares two ways of deciding when heart surgery patients need a blood transfusion in the ICU. One uses a fixed blood count threshold, while the other also considers each patient's oxygen and lactate levels. The goal is to see if the personalized approach is as safe an…

This study tests whether eating goat liver three times a week can improve anemia in teenage girls in Nepal, compared to standard iron-folic acid pills. Researchers will also look at how gut bacteria affect iron absorption. Sixty girls aged 15-19 with anemia will be randomly assig…

This study tests whether using cord blood, rich in fetal hemoglobin, for transfusions in preterm infants can reduce serious complications like blindness, lung disease, and gut problems. Researchers will compare outcomes in 200 very low birth weight babies who receive either cord …

This study tests whether dapagliflozin, a drug used for diabetes, can help treat anemia in people with lower-risk myelodysplastic syndromes (MDS). Anemia is a common problem in MDS, causing fatigue and often requiring blood transfusions. The trial will give 37 participants dapagl…

This phase 3 trial in Bangladesh will test whether ferric citrate, a different form of iron, works better and causes fewer stomach problems than the standard ferrous fumarate for pregnant women with moderate to severe iron deficiency anemia. 680 women aged 18-35 in their second t…

This study will test whether SGLT2 inhibitors, a type of diabetes drug, can help correct anemia in people with chronic kidney disease (CKD). Anemia is common in CKD and often requires iron or hormone injections, which have side effects. The trial will enroll 60 adults with CKD st…

This study tests whether giving a combination of intravenous iron, erythropoietin (EPO), and tranexamic acid before bone tumor surgery can improve hemoglobin levels and reduce the need for blood transfusions compared to usual care. The trial enrolls 160 adults with anemia or iron…

This study tests whether health education delivered by mobile phone can improve hemoglobin levels in pregnant women with mild to moderate anemia in rural Bangladesh. About 132 women will be split into two groups: one receives regular care plus mobile messages and calls about diet…

This study compares an oral iron supplement (sucrosomial iron) to the usual intravenous (IV) iron given to anemic patients before heart surgery. About 75 adults with mild anemia scheduled for heart procedures will be randomly assigned to one of the two treatments. The goal is to …

This study looks at whether roxadustat, a drug for anemia in chronic kidney disease, can also help people with heart failure. Researchers will review medical records of 200 patients who took roxadustat for at least a year. They will check heart function, symptoms, and major event…

This study tests whether giving a single dose of intravenous iron the day after heart surgery can reduce the chance of long-term anemia. About 180 adults with low iron or anemia before surgery will be randomly assigned to receive either the iron treatment or a placebo. The main g…

This study tests whether adding levocarnitine injections to standard care can lower the amount of anemia medication needed by people on hemodialysis. About 94 adults with kidney failure and anemia will receive either levocarnitine after each dialysis session or usual care alone f…

This study tests whether a non-invasive device that uses light to measure hemoglobin through the skin can accurately detect anemia. Researchers will compare its readings with standard blood tests in 150 adults in Jakarta. If the device proves reliable, it could offer a quick, pai…

This study tests whether giving iron supplements to older adults (75+) after hip fracture surgery can reduce fatigue and improve recovery. 528 participants will receive either intravenous iron, oral iron pills, or a placebo. The goal is to see if iron helps with energy, mobility,…

This study asks whether the standard blood hemoglobin concentration accurately reflects the body's true oxygen-carrying capacity in adults with non-life-threatening anemia arriving at the emergency department. Participants will undergo additional tests, including a carbon monoxid…

This study in Côte d'Ivoire tests whether giving mothers a cash reward for breastfeeding until their child is 24 months old increases breastfeeding rates and improves child and maternal health. About 1,040 mothers will either receive the cash incentive or just educational materia…

This study will check how common parasitic infections are in 285 people with blood disorders, like anemia or blood cancers, at Assiut University hospitals in Egypt. Researchers will test for Toxoplasma and other parasites. The goal is to understand if routine screening could help…

This study looks at how different types of anemia—like iron deficiency or thalassemia—can change HbA1c levels, a common test for diabetes, in people who do not have diabetes. Researchers will compare HbA1c results between 100 non-diabetic adults with various anemias and a healthy…